PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus Abbey L. Perl ,Jennifer L. Koetsier &Kathleen J. Green Article 31 July 2023|Open Access Activation of cAMP (EPAC2) signaling pathway promotes hepatocyte attachment ...
Uptake of small extracellular vesicles by recipient cells is facilitated by paracrine adhesion signaling Hirosawa et al. use single particle tracking and superresolution imaging to demonstrate that tumor-derived small extracellular vesicles (sEVs) undergo clathrin-independent endocytosis, with some using cav...
Cellular biology A novel signaling pathway that governs cell adhesion RENSSELAER POLYTECHNIC INSTITUTE Andrea Page-McCaw ZhangShuningMMPs (Matrix Metalloproteinases) are a family of extracellular proteases. They can mediate tissue remodeling. Their main function is to cleave substrates including extracellular...
(e.g., EGFR) destabilize cell adhesion through β-cat phosphorylation at tyrosine residues (P).2)Intracellular signaling and gene transcription activation. Wnt signals stabilize β-cat by blocking its intracellular degradation (see also point 3) and lead to nuclear translocation. In the nucleus, ...
The inhibition of PI 3-kinase has been shown to lead to VCAM-1 expressiondownregulationand loss of monocyte-endothelial cell adhesion inanimal models. Additional attention was provided to the PI 3-kinase/protein kinase Bsignaling pathway, as it is involved in cellular differentiation and was previo...
8. Determination of single-molecule loading rate during mechanotransduction in cell adhesion (在细胞粘附过程中力学转导单分子加载速率的测定) Cell Weekly 滑动阅览 1. A gut-derived hormone regulates cholesterol metabolism (一种源自肠道...
Adhesion is required for cell communication and regulation, as well as for the development and maintenance of tissues. Adhesion is also required for the formation of new tissues. Cell adhesion is defined as a cell’s ability to adhere to another cell or an extracellular matrix (ECM). (Khalili...
登录 注册 待分类 > 待分类 > 《Cell》最新细胞信号通路大全 Tight and Adherens Junction Signaling and Wnt-β-Catenin Signaling 下载文档 收藏 打印 转格式 865阅读文档大小:2.77M5页医学吧上传于2013-05-28格式:PDF
巨核细胞和中性粒细胞形成emperipolesis的过程由β-整合素、细胞间黏附分子1 (intercellular adhesion molecule-1, ICAM-1)和ezrin介导的黏附开始,随后中性粒细胞进入巨核细胞的细胞质并驻留在囊泡中。囊泡的膜被溶解,将中性粒细胞释放到宿主的细胞质...
2023年3月9日,华东师范大学生命科学学院江文正教授团队在Cell & Bioscience上发表题为"GPR116 receptor regulates the antitumor function of NK cells viaGαq/HIF1α/NF-κBsignaling pathway as a potential immune checkpoint"的研究。该研究通过体外和体内实验证明GPR116受体能够通过Gαq/HIF1α/NF-κB途径负调...