基因名全称 Monocyte differentiation antigen CD14 Uniprot ID P10810 检测种属 小鼠 显色方法 TMB显色 保存温度 2～8℃ 有效期 6个月 洗板方法 手工/自动 检测方法 夹心酶联免疫吸附法 检测仪器 标准规格酶标仪 可售卖地 北京;天津;河北;山西;内蒙古;辽宁;吉林;黑龙江;上海;江苏;浙江;安徽;福建;...
The Effect of Honey Bee Venom on CD14 Protein Expression as Monocyte Marker in D-Alpha-Tocopheryl Succinate (Vitamin E)-Treated HL-60 CellsBackground: The membrane form of a Cluster of Differentiation 14 (CD14) is anchored to the phospholipid bilayer via glycosylphosphatidylinositol anchor. This ...
CD14基因编码的蛋白,优先表达于单核/巨噬细胞。CD14是革兰阴性菌内毒素脂多糖LPS和LPS结合蛋白(LBP)复合物的高亲和力受体。CD14识别并结合LPS,引起细胞酪氨酸磷酸化、核因子NF-κB转位、触发细胞因子释放和氧自由基产生,在机体免疫、防御系统引起的一系列反应中发挥重要作用。 1. CD14的发现 1981年,Todd首次从人单...
2b), each with unique signature genes (selected marker genes shown in Supplementary Fig. S2a and b, Supplementary Table S2). There were conspicuous disparities in the distribution of cell subset ratios among individual patients (Fig. 2c). Fig. 2 Monocyte-related gene signature enriched in the...
CD14基因编码的蛋白,优先表达于单核/巨噬细胞。CD14是革兰阴性菌内毒素脂多糖LPS和LPS结合蛋白(LBP)复合物的高亲和力受体。CD14识别并结合LPS,引起细胞酪氨酸磷酸化、核因子NF-κB转位、触发细胞因子释放和氧自由基产生,在机体免疫、防御系统引起的一系列反应中发挥重要作用。
Furthermore, endothelial dysfunction was associated with higher expression of activation marker CD11c selectively on CD14+CD16++monocytes. Nonclassical and classical monocyte frequencies remained independent predictors of endothelial dysfunction when major risk factors for atherosclerosis were taken into account ...
Monocyte-rich plaques are also more vulnerable and prone to overimposed thrombosis [20]. In fact, inflammatory cytokines such as TNFα or interleukins strongly induce the expression of both full-length TF as well as alternatively spliced TF (asTF) in endothelial and blood cells [21,22]. ...
Mean levels of the monocyte-specific activation marker sCD14 in cases and controls were not different in our study. As a consequence, the OR for the presence of CAD in the top quintile of the sCD14 distribution was not significantly increased in multivariable analysis, compared with the bottom...
Monocyte differentiation antigen CD14 is a 55-kDa protein that is expressed in two forms: glycosylphosphatidylinositol-anchored membrane form (mCD14) and a soluble form (sCD14)[98,99]. mCD14 is mainly expressed in myeloid cells, whereas sCD14 is secreted from other type of cells, such as...
Carotid intima media thickness (CIMT) was used as atherosclerosis marker. The monocyte subsets were characterized by flow cytometry and isolated by immuno-magnetic selection. Proinflammatory cytokines, peroxides levels and cellular activation markers were analyzed. NanoString nCounter miRNA Expression Array ...