CD14++CD16− and CD14+CD16+ monocyte subsetsendothelial celladhesioncytokineBased on the difference in the CD14 and CD16 expression, two subsets of monocytes were identified in human and other mammalian blood. These subsets have different patterns of adhesion molecules and chemokine receptors that ...
Monocyte subset analysis by flow cytometry has been shown to be a useful diagnostic tool in chronic myelomonocytic leukemia in adults. An increase in the classical monocyte fraction (CD14++/CD16) greater than 94.0% of total monocytes is considered highly sensitive and specific in distinguishing ...
目的采用孟德尔随机化(MR)分析探究表达程序性死亡受体配体1(PD-L1)的CD14 ++CD16 +单核细胞与急性呼吸窘迫综合征(ARDS)之间的因果关系。 方法以表达PD-L1的CD14 ++CD16 +单核细胞为暴露因素,以ARDS为结局因素。通过全基因组关联分析数据库获取单核苷酸多态性(SNP)作为工具变量。表达PD-L1的CD14 ++CD16 +单...
Monocyte subsets Characteristic CD14 CD16 高水平的CD14分子, 是较为特异的表面标志。而 CD14+CD16+单核细胞是一群独特的单核细胞。这群 细胞与经典的单核细胞比较,其细胞表面分子有不同的特征。在人类,经典的CD14++CD16-单核细胞表达 CCR2,CD64,CD62L,CD14+CD16+单核细胞则不表达 ...
已知的主要根据 CD14和 CD16 抗原的表达分为 4 个亚型: CD14 ++ CD16 -( G1亚型), CD14 ++ CD16 + ( G2 亚型), CD14 + CD16 -( G3 亚型), CD14 + CD16 + ( G4 亚型)。其中最主要的有 2 型,其一我们已知的 CD14 强阳性的 ( CD14 ++ CD16 - 单核细胞) 经典的单核细胞外, 另一型...
CD14 is expressed on monocytes, interfollicular macrophages and some dendritic cells. Complexes of LPS and LBP (LPS-Binding Protein) bind with high affinity to monocytes through the surface CD14.Applications Reported: This MEM-15 antibody has been reported for use in flow cytometric analysis....
Based on the difference in the CD14 and CD16 expression, two subsets of monocytes were identified in human and other mammalian blood. These subsets have different patterns of adhesion molecules and chemokine receptors that suggests the different mode of their interaction with endothelium and tissue tr...
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CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form....
HLA-DR expression was decreased on each subtype of monocyte of NHL patients, among which the difference of intermediate monocyte (CD14 ++CD16 +) (25.43 MFI vs. 33.52 MFI, P<0.01) and non-classical monocyte (CD14 +CD16 ++) (11.40 MFI vs. 15.70 MFI, P< 0.01) were of statistical ...