Blood monocyte subpopulations have been defined in man initially, and the two major types of monocytes are the CD14++ CD16- and the CD14+ CD16+ monocytes. These cells have been shown to exhibit distinct phenotype and function, and the CD14+ CD16+ were labeled...
The frequency of CD14+ monocytes was significantly decreased, while the CD14+CD16+ monocyte population was significantly expanded during ZIKV infection compared to uninfected controls. Viral RNA was detected in PBMCs from all patients, but in serum from only a subset, suggesting PBMCs may be a ...
The CD14+/lowCD16+ monocyte subset is more susceptible to spontaneous and oxidant-induced apoptosis than the CD14+ CD16- subset. Cell Death Dis 2010; 1, e95.Zhao C, Tan YC, Wong WC, Sem X, Zhang H, Han H, Ong SM, Wong KL, Yeap WH, ...
结论:外周血 CD14+CD16+单核细胞亚群参与类风湿性关节炎发病,其比值可作为疾病活动性参考指标。 关键词:CD14+CD16+,单核细胞;类风湿性关节炎;流式细胞术 中图分类号:R593 文献标识码:A 文章编号:1671-5675(2018)02-0187-02 单核细胞(monocyte,Mo)是具有多种作用的固有免疫细胞,能参与抗原呈递、调控 T ...
Heterogeneity of human blood monocytes: the CD14+ CD16+ subpopulation. Previously, human blood monocyte subpopulations were defined by approaches that required their isolation, such as differential sedimentation or adherence. ... HWL Ziegler-Heitbrock - 《Immunology Today》 被引量: 675发表: 1996年 ...
In vitro induction of maturation of blood monocytes by 5 day culture of peripheral blood mononuclear cells in 10 % human serum will result in decreased CD14 and increased CD16 cell surface expression on the monocyte derived macrophages. At the same time, these cells acquire increased levels of ...
Nonclassical and classical monocyte frequencies remained independent predictors of endothelial dysfunction when major risk factors for atherosclerosis were taken into account (β =0.18 p=0.04 and β =-0.19 p=0.03, respectively). In summary, our data indicate that CD14+CD16++"nonclassical" monocytes ...
CD14+CD16+ and CD14+CD163+ monocyte subpopulations in kidney allograft transplantation. Sekerkova A,Krepsova E,Brabcova E, et al. BMC Immunology . 2014Sekerkova A, Krepsova E, Brabcova E, et al. CD14+CD16+ and CD14+CD163+ monocyte subpopulations in kidney allo- graft transplantation. ...
Different functions of monocyte subsets in familial hypercholesterolemia: potential function of CD14+CD16+ monocytes in detoxification of oxidized LDL We conclude that FH-CD14(+)CD16(+) monocytes have specialized functions in the uptake of oxLDL at activated endothelial cell surfaces, and we ... ...
Characterization of the CD14++CD16+ Monocyte Population in Human Bone Marrow Numerous studies have divided blood monocytes according to their expression of the surface markers CD14 and CD16 into following subsets: classical CD14(++)CD16(-), intermediate CD14(++)CD16(+) and nonclassical CD14(+)CD...