N418单克隆抗体与小鼠CD11c反应,CD11c是小鼠树突状细胞(DC)最广泛使用的标志物。CD11c也被称为整合素α-X(Itgax)和CD11抗原样家族成员C。CD11c是整合素α链家族的150 kDa单程I型膜蛋白,其相关成员包括CD11a(LFA-1)、CD11b(MAC-1)和CD11d(D)。在序列同源性、表达谱和配体的背景下,CD11c与CD11b和CD11d基本相似。
CD11c+CD11b+ dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune encephalomyelitis. J Immunol. 2008;181(4):2483-2493.Li H, Zhang GX, Chen Y, Xu H, Fitzgerald DC, Zhao Z, Rostami A. CD11c+CD11b+ dendritic cells...
N418单克隆抗体与小鼠CD11c反应,CD11c是小鼠树突状细胞(DC)最广泛使用的标志物。CD11c也被称为整合素α-X(Itgax)和CD11抗原样家族成员C。CD11c是整合素α链家族的150 kDa单程I型膜蛋白,其相关成员包括CD11a(LFA-1)、CD11b(MAC-1)和CD11d(D)。在序列同源性、表达谱和配体的背景下,CD11c与CD11b和CD11d基本相似。
N418单克隆抗体与小鼠CD11c反应,CD11c是小鼠树突状细胞(DC)最广泛使用的标志物。CD11c也被称为整合素-X(Itgax)和CD11抗原样家族成员C。CD11c是整合素链家族的150 kDa单程I型膜蛋白,其相关成员包括CD11a(LFA-1)、CD11b(MAC-1)和CD11d(D)。在序列同源性、表达谱和配体的背景下,CD11c与CD11b和CD11d基本相似。C...
CD207 (langerin) Microbeads 小鼠脾脏 Pan DC细胞 Markers: MHC class II+,CD11c+,CD11b+/–,F4/80– 分选试剂: CD11c Microbeads ultrapure, Pan DC microbeads, Pan Dendritic cell isolation kit pDC细胞 Markers: MHC class II+,PDCA-1 (BST2)+,SiglecH+,B220 (CD45R)+,CD11b– ...
Depletion of CD11c+CD11b+ DCs also precluded i.v. autoantigen-induced T-cell tolerance, such as decreased production of IL-2, IFN-γ, IL-17 and numbers of IL-2+, IFN-γ+, and IL-17+ CD4+ T cells, as well as an increased proportion of CD4+CD25+Foxp3+ regulatory T cells and ...
Integrin alpha X beta 2 is expressed on macrophages, dendritic cells, hairy cell leukemias and some other leukocyte subsets. The 1097 aa mouse CD11c extracellular domain shares 71% and 87% amino acid (aa) identity with human and rat CD11c, respectively. One potential alpha X isoform is ...
CD11c+CD11b+ Dendritic Cells Play an Important Role in Intravenous Tolerance and the Suppression of Experimental Autoimmune Encephalomyelitis1 Li H,Zhang GX,Chen Y,et al.CD11c+CD11b+dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune ...
Following intragastric inoculation of cyst-containing parasites in mice, CD11c+ dendritic cells from the intestinal lamina propria, the Peyer patches, and the mesenteric lymph nodes were parasitized while in the blood, parasites were associated with the CD11c- CD11b+ monocytes. Using adoptive transfer...
CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent ...