激动结合诱导表达是否可行? 或者相较于极易引发不可控效应的激动剂,诱导更高水平的CD11b表达是否能成为“激动”CD11b的另类方法? 参考资料 Thacker G et al. Immature natural killer cells promote progression of triple-negative breast cancer. Sci Transl Med. 2023 Mar 8;15(686):eabl4414. Linde IL et a...
Heo SK等研究表明，AML患者的骨髓中CD133细胞高表达，在分离自AML和慢性髓细系白血病（chronic myeloid leukemia,CML）患者的骨髓培养中显著检测到白血病干细胞（leukemia stem cells,LSC），研究结果说明AML中的CD133细胞潜在地充当了LSC。CD11b在白血病的原始细胞、自然杀伤细胞、成熟的单核细胞、粒细胞中表达，分布在...
CD133作为HSOC表面抗原,在正常以及异常的造血组织和非造血组织中,均有表达,随着细胞的分化,CD133的表达会减弱,甚至是消失。Heo SK等研究表明,AML患者的骨髓中CD133细胞高表达,在分离自AML和慢性髓细系白血病(chronic myeloid leukemia,CML)患者的骨髓培养中显著检测到白血病干细胞(leukemia stem cells,LSC),研究结果...
或者相较于极易引发不可控效应的激动剂,诱导更高水平的CD11b表达是否能成为“激动”CD11b的另类方法? 基础免疫-流式试剂 参考资料 Thacker G et al. Immature natural killer cells promote progression of triple-negative breast cancer. Sci Transl Med. 2023 Mar 8;15(686):eabl4414. Linde IL et al. Neu...
Heo SK等研究表明,AML患者的骨髓中CD133细胞高表达,在分离自AML和慢性髓细系白血病(chronic myeloid leukemia,CML)患者的骨髓培养中显著检测到白血病干细胞(leukemia stem cells,LSC),研究结果说明AML中的CD133细胞潜在地充当了LSC。 CD11b在白血病的原始细胞、自然杀伤细胞、成熟的单核细胞、粒细胞中表达,分布在骨髓...
36 INVITED CD11b Cells Provide Resistance to Radiotherapydoi:10.1016/S0959-8049(11)70251-9M.BrownandG.AhnandR.AlOmranandSDOSEuropean Journal of Cancer
免疫原 B10 mouse spleen cells enriched for T cells 应用 in vivo CD11b neutralization/ILC2 cell purification/Flow cytometry 产品形式 PBS , pH 7.0 Contains no stabilizers or preservatives 内毒素水平 <2EU/mg (<0.002EU/μg) 使用 LAL gel clotting 测定 纯度 >95% Determined by SDS-PAGE ...
参考文献:Hänninen, Arno et al. “Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes.” European journal of immunology vol. 41,3 (2011): 634-44. doi:10.1002/eji.201040760 Fleming, T J et al. “Sel...
functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 ...
CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. STAT6-mediated chemokine production in the lung is required for Th2 lymphocyte and eosinophil homing into the airways in allergic pulmonary inflammation, a... Medoff,Seung,Hong,... - 《Jou...