激动结合诱导表达是否可行? 或者相较于极易引发不可控效应的激动剂,诱导更高水平的CD11b表达是否能成为“激动”CD11b的另类方法? 参考资料 Thacker G et al. Immature natural killer cells promote progression of triple-negative breast cancer. Sci Transl Med. 2023 Mar 8;15(686):eabl4414. Linde IL et a...
所以Gr1+ CD11b-细胞可能CD8是阳性的,如果补做CD8是阳性的话,则可证实是细胞毒T细胞。 如果你还有问题,或有什么需要补充的意见,欢迎留言或点击“阅读原文”跳至论坛上讨论。 参考文献:Hänninen, Arno et al. “Ly6C supports preferential homing of ...
Heo SK等研究表明，AML患者的骨髓中CD133细胞高表达，在分离自AML和慢性髓细系白血病（chronic myeloid leukemia,CML）患者的骨髓培养中显著检测到白血病干细胞（leukemia stem cells,LSC），研究结果说明AML中的CD133细胞潜在地充当了LSC。CD11b在白血病的原始细胞、自然杀伤细胞、成熟的单核细胞、粒细胞中表达，分布在...
CD133作为HSOC表面抗原,在正常以及异常的造血组织和非造血组织中,均有表达,随着细胞的分化,CD133的表达会减弱,甚至是消失。Heo SK等研究表明,AML患者的骨髓中CD133细胞高表达,在分离自AML和慢性髓细系白血病(chronic myeloid leukemia,CML)患者的骨髓培养中显著检测到白血病干细胞(leukemia stem cells,LSC),研究结果...
Inflammatory dendritic cells restrain CD11b+CD4+CTLs via CD200R in human NSCLC Britton Donato,Mayo Clinic Arizona, Phoenix, AZ, 背景: CD4+细胞毒性T淋巴细胞(CD4+CTL)是一种新的CD4+T细胞亚群,具有直接通过细胞毒性杀死...
Heo SK等研究表明,AML患者的骨髓中CD133细胞高表达,在分离自AML和慢性髓细系白血病(chronic myeloid leukemia,CML)患者的骨髓培养中显著检测到白血病干细胞(leukemia stem cells,LSC),研究结果说明AML中的CD133细胞潜在地充当了LSC。 CD11b在白血病的原始细胞、自然杀伤细胞、成熟的单核细胞、粒细胞中表达,分布在骨髓...
Kobayashi M,Yoshida T,Takeuchi D, et al.Gr-1(+)CD11b(+) cells as an accelerator of sepsis stemming from Pseudomonas aeruginosa wound infection in thermally injured mice. Journal of Leukocyte Biology . 2008Kobayashi, M (2008) Gr-1(+)CD11b(+) cells as an accelerator of sepsis stemming ...
functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 ...
functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 ...
cells. Applications Reported: The CBRM1/5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This CBRM1/5 antibody has been pre-titrated and tested by flow cytometric analysis of resting and activated normal human peripheral blood cells. This ca...