Granulocytes and Subsets, Monocytes, Myeloid Cells Species Mouse Sample Source Bone Marrow, Other, Whole Blood Selection Method Negative Application Cell Isolation Brand EasySep Area of Interest Immunology View More Data Figures Figure 1.Typical EasySep™ Mouse MDSC (CD11b+Gr1+) Cell Isolation Profile...
CD11b(+) Gr1(+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice . Hepatology 2012; 56 :1902–12. doi:10.1002/hep.25817Suh YG, Kim JK, Byun JS, Yi HS, Lee YS, Eun HS, et al. CD11b+ Gr1+ bone marrow cells ameliorate liver fibrosis by producing ...
答:Gr-1单抗通常认为是粒细胞标记,但实际上,它既可结合Ly-6G也可结合Ly-6C。大多数 Gr1+ CD11b- 细胞是 Ly6C+ LyG-,Ly6C可表达在浆细胞、部分粒细胞和T 细胞(包括记忆 T 细胞)表达。所以Gr1+ CD11b-细胞可能CD8是阳性的,如果补做CD8是阳性的...
Gr1(+)CD11b(+) cells expressed high levels of arginase-1, and IL-17, additional markers of myeloid derived suppressor cells. We then sorted the Gr1(hi) and Gr1(int) populations from M. tuberculosis infected NOS-/- mice and placed the sorted both Gr1(int) populations at different ratios ...
CD11b+ Gr1dim cells were transferred to ZyA-treated SKG mice.MDSCs, Th17 cells, and group 1 and 3 innate lymphoid cells (ILC1s and ILC3s) were increased in the lungs; the proportion of these cells varied with ILD severity. In this process, we found that a unique cell population, CD...
采用小鼠4T1乳腺癌模型观察MSC通过CD11b+Gr1+细胞对肿瘤生长的影响.结果 MSC能够促进骨髓中CD11b+Gr1+细胞的存活和生成,同时可诱导正常小鼠骨髓中CD11b+Gr1+细胞对T细胞的抑制作用.动物实验结果显示,MSC处理后的骨髓CD11b+Gr1+细胞可以促进肿瘤的生长,加速小鼠的死亡.结论 MSC可以通过促进骨髓来源的CD11b+Gr1+细胞...
Studies have shown that bone marrow-derived cells play an important role in tumor recurrence after chemotherapy and radiotherapy. In this study, we examined the relationship between the accumulation of Gr-1+CD11b+ cells and tumor recurrence after irradia
CD11b(+) Gr1(+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice. Hepatology. 2012;56(5):1902-12.Suh YG, Kim JK, ... H.-S.,Duester,Y.-S.,... 被引量: 0发表: 0年 CD11B + Gr1 + BMCs ameliorate liver fibrosis by producing interleukin-10 in mice...
To characterize each population further, the cells were sorted as shown (Figure 1b). As expected, the Gr1hi population showed myleoperoxidase activity characteristic of neutrophils but the Gr1int cells did not express myleoperoxidase (Figure 1c). The cells were also examined for the expression ...
CD11b + Gr1+ cells were isolated from these splenocytes, and labeled with fluorchrome-conjugated anti-Ly-6 G and anti-Ly-6 C antibodies. FACS analysis was performed to determine the percentage of each cell population. Results are presented as mean values (N = 5) ± ...