Kallberg E, Stenstrom M, Liberg D, Ivars F, Leanderson T. CD11b+ Ly6C++ Ly6G-cells show distinct function in mice with chronic inflammation or tumor burden. BMC Immunol 2012; 13: 69.Kallberg E, Stenstrom M, Liberg D, Ivars F, Leanderson T (2012) CD11b+ Ly6C++Ly6G- cells show ...
骨髓来源的抑制性细胞(Myeloid-derived suppressor cells，MDSCs)是骨髓来源的一群异质性细胞，是树突状细胞(dendritic cells，DCs)、巨噬细胞和(或)粒细胞的前体，具有显著抑制免疫细胞应答的能力。小鼠MDSCs的表型为CD11b+Gr-1+，分两个亚型:粒细胞样的MDSCs(CD11b+Ly6C-Ly6G+)和单核细胞样的MDSCs...
骨髓来源的抑制性细胞(Myeloid-derived suppres洋战尼行sor cells,MDSCs)是骨髓来源的一群异质性细胞,是树突状细胞(dendritic cells,DCs)、巨噬细胞和(或)粒细胞的前体,具有显著抑制免富烈绍学治盾济条免疫细胞应答的能力。 小鼠MDSCs的表型为CD11b+Gr-1+,分两个亚型:粒细胞样的MDSCs(CD11b+Ly6C-Ly6G+)和...
CD11b+, Ly6G+ cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathogens . 2011; 7 (11)... MA Fischer,ML Davies,IE Reider,... - 《Plos Pathogens》 被引量: 66发表: 2011年 Immunosuppression during acute Trypanosoma cruzi infectio...
S100A9 has been shown to be important for the function of so called Myeloid Derived Suppressor Cells (MDSC). Cells with a similar phenotype are also involved in pro-inflammatory processes, and we therefore wanted to investigate the gene expression and fu
(IL) 7R+and granzyme B+T cells in the tumor microenvironment. Interestingly, we observed that Ly6GlowG-MDSC sharply decreased after fasting treatment, and the cell surface markers and protein mass spectrometry data showed ...
cells show distinct function in mice with chronic inflammation or tumor burden Stenstrom M, Liberg D, Ivars F, Leanderson T (2012) CD11b+Ly6C++Ly6G- cells show distinct function in mice with chronic inflammation or tumor burden... E Kallberg,M Stenstrom,D Liberg,... 被引量: 23发表: ...
Tumors contain CD11b+Ly6G+ cells, known as granulocytic myeloid-derived suppressor cells (G-MDSCs) or tumor-associated neutrophils (TANs) that play a critical role in tumor progression and development. Here, we demonstrate that CD11b+Ly6G+ cells respond to polyI:C and exhibit tumoricidal ...
FSC-W cells excluded doublet cells. Ly6g-phycoerythrin was then used to negatively gate out all neutrophils, and all lymphocytes were gated out based on their lower FSC-A and SSC-A profile. This allowed FACS analysis on the remaining MΦ/monocyte subpopulations. AMΦs were discriminated from...
在进行细胞表面分子染色前,用CD16/CD32抗体孵育细胞悬液封闭细胞表面的Fc受体。用于检测细胞表面蛋白的抗体包括:购自ebioscience的CD3e、CD4、CD8a、CD19、NK1.1、F4/80、CD45、CD11b、CD45.1、CD45.2、Ki67、Ly6C和购自biolegend的CD115、Ly6G、和Siglec-F。IL4Rα抗体购自R&D。