CD1C+ B dendritic cellsCD8+ T cellsmicroglial cellsrenal clear cell carcinomatumor microenvironmentRenal clear cell carcinoma (RCC) is a type of malignant tumor, which, in addition to surgical resection, radiotherapy, and chemotherapy, has been widely treated through immunotherapy recently. However, ...
在血液中,除了骨髓树突细胞外,一小部分静息B细胞表达CD1c(BDCA-1)。因此,CD1c(BDCA-1)+树突细胞分离试剂盒包括CD19微珠,用于在富集CD1c(BDCA-1)+骨髓树突细胞之前去除B细胞。为了区分CD1c(BDCA-1)+与CD141(BDCA-3)+骨髓树突细胞,它们被指定为1型髓样树突细胞(MDC1s)或常规DC2细胞(cDC2s)。
C Caux, B Vanbervliet, C Massacrier, et al. CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha. J Exp Med, 184 (2) (1996), pp. 695-706 View in ScopusGoogle Scholar 15 D Strunk, K Rappersbe...
Authors Andrew J Kassianos, Melinda Y Hardy, Xinsheng Ju, Dipti Vijayan, Yitian Ding, Annelie J E Vulink, Kylie J McDonald, Sarah L Jongbloed, Robert B Wadley, Christine Wells, Derek N J Hart, Kristen J Radford Dendritic Cell Program, Mater Medical Research Institute, South Brisbane, Qu...
(also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal...
Description: This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zo...
Dendritic cell development: a choose-your-own-adventure story Human group 1 CD1 molecules, CD1a, CD1b and CD1c, bind microbial glycolipids as well as self-glycolipids including GM1, and present the antigens to T-cells and NKT cells. Guillain-Barre syndrome and anti-ganglioside antibodies: a ...
BMC Infectious Diseases (2015) 15:342 DOI 10.1186/s12879-015-1092-8 RESEARCH ARTICLE Open Access Low CD1c + myeloid dendritic cell counts correlated with a high risk of rapid disease progression during early HIV-1 infection Yingying Diao1, Wenqing Geng2,3, Xuejie Fan2,3, Hualu Cui2,3, ...
Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens The characterization of human dendritic cell (DC) subsets is essential for the design of new vaccines. We report the first detailed functional analysis of ... SL ...
- 《Cytometry Part B Clinical Cytometry》 被引量: 0发表: 2015年 Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses. Dendritic cells (DC) have the unique capacities to induce primary T-cell responses. In mice, CD8 alpha+DC are specialized...