小部分CD1c(BDCA-1)+髓系树突状细胞表达CD14和CD11b。CD1c(BDCA-1)还表达于体外从单核细胞或造血祖细胞生成的CD1a+ DCs上。在血液中,除了髓样DC外,一个B细胞亚群亦表达CD1c(BDCA-1),为此,CD1c(BDCA-1) + DC分选试剂盒中备有CD19 微珠,用于在富集CD1c(BDCA-1)+DC前去除B细胞。为了区分CD1c(...
CD1c(BDCA-1)+树突细胞分离试剂盒开发用于从PBMC分离CD1c(BDCA-1)+髓样树突细胞(MDC; 1型MDC或cDC2)。这种新的形式允许有选择地去除最近已经显示可能会污染最终DC群体的CD14+骨髓细胞。 CD1c(BDCA-1)抗原在树突细胞上特异性表达,并且CD11chighCD123low代表人血液中骨髓树突细胞的主要亚组。 CD1c(BDCA-1)...
CD1c(BDCA-1)+树突细胞分离试剂盒开发用于从PBMC分离CD1c(BDCA-1)+髓样树突细胞(MDC; 1型MDC或cDC2)。这种新的形式允许有选择地去除最近已经显示可能会污染最终DC群体的CD14+骨髓细胞。 CD1c(BDCA-1)抗原在树突细胞上特异性表达,并且CD11chighCD123low代表人血液中骨髓树突细胞的主要亚组。 CD1c(BDCA-1)...
CD1c(BDCA-1)+树突细胞富集试剂盒包括FcR阻断试剂,CD1c(BDCA-1)-PE,抗PE磁珠,用于富集CD1c(BDCA-1)+血液树突细胞。包括CD20磁珠用于在DC分离之前去除B细胞。 人和恒河猴树突细胞代表是由几个亚群组成的异源群体。髓样和浆细胞样DC通过表达CD11c和CD123的细胞分别分化而成。这些细胞通过针对人血液树突细胞抗原...
C Caux, B Vanbervliet, C Massacrier, et al. CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha. J Exp Med, 184 (2) (1996), pp. 695-706 View in ScopusGoogle Scholar 15 D Strunk, K Rappersbe...
CD1c+ blood dendritic cells have Langerhans cell potential Langerhans cells (LCs) are self-renewing in the steady state but repopulated by myeloid precursors after injury. Human monocytes give rise to langerin-positive cells in vitro, suggesting a potential precursor role. However, differentiati......
BMC Infectious Diseases (2015) 15:342 DOI 10.1186/s12879-015-1092-8 RESEARCH ARTICLE Open Access Low CD1c + myeloid dendritic cell counts correlated with a high risk of rapid disease progression during early HIV-1 infection Yingying Diao1, Wenqing Geng2,3, Xuejie Fan2,3, Hualu Cui2,3, ...
The current definition of myeloid dendritic cell CD1c-positive (CL:0002399) is “A myeloid dendritic cell found in the blood that is CD1c-positive.” If we remove "found in the blood" the term can be use for tissue resident dendritic cells as well. New definition would be “A myeloid ...