此外,通过调节TAM中的CD11b信号传导,GB1275能够增加干扰素相关因子(IFNα1、IFNβ、CXCL9和CXCL10)和抗原呈递/共刺激复合物(MHC-I、MHC-II、CD80和CD86)的表达水平,同时降低免疫抑制基因(IL10、TGFβ和精氨酸酶-1)的表达,因此,GB1275对CD11b的变构调节导致TAM极化向促炎和抗原呈递表型的转变,增强干扰素反应并...
7. 小鼠肠道组织 肠道组织里,很多老师都会研究DC细胞,但是DC细胞的标志物CD11C,MHCII在肠道巨噬细胞中也会有表达,老师们在检测和数据分析圈门时要注意哦。 8. 小鼠皮肤组织 除了CD11B,F4/80marker外,可添加EPCAM,CD64,CD24等标...
Conventional APCs that express MHC class II (MHCII) and co‐stimulatory molecules include dendritic cells (DCs) and macrophages. Beyond these conventional APCs, immune stimulatory cells have been more recently shown to extend to a class of atypical APCs, composed of mast cells, basophils, and eos...
PIERCE MA180312 Anti-MHC II Monomorphic Monoclonal Antibody, RPE conjugate 100 Tests 5783 PIERCE MA180313 Anti-MBP Monoclonal Antibody 2 ml 3978 PIERCE MA180314 Anti-CD11c Monoclonal Antibody 250 µg 3384 产品留言 标题 联系人 联系电话 内容 验证码 点击换一张 注:1.可以使用快捷键...
Clinically Relevant Allergen Mixture Induces Robust Immune Response By Increasing CD11c+CD11b+MHCIIhiCD103int Lung Dendritic CellsSannette C. HallDevendra K. AgrawalElsevier BVJournal of Allergy and Clinical Immunology
Small-molecule MHC-II inducers promote immune detection and anti-cancer immunity via editing cancer metabolism Authors - Ling Huang View Article mouse FC Cell Commun Signal Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage Authors - ...
与Ly6GhighG-MDSC亚群相比,在所有66个使用的标记物中,只有CXCR4、F4/80、MHC II和CD205在Ly6GlowG-MDSC中高表达(图4C)。此外,对Ly6Glow和Ly6Ghigh的G-MDSC亚群进行分类,通过质谱检测蛋白表达差异(图4D1)。研究发现,与Ly6GlowG-MD...
2.Baca Jones, C.C. (2009) Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells. Virology. 388: 78-90. 3.Clark, A.K. et al (2007) Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain. ...
Further characterization of CD11bhighCD11cpos immune cells (subset M) in mouse BAL profiles (Figure 2a) showed that these were lung monocytes with increased MHC Class II, CD14, and CD86 surface expression compared with AMΦs (Figure 2b). MHC Class II is heterogeneously expressed on lung monocy...
Thus, conventional DCs are sufficient to driveS. mansoniegg antigen-specific immune responses in the intestinal draining lymph nodes, and process and present egg antigens to CD4 T cells in a MHCII-dependent manner. SEA treatment of DCs does not affect IRF-4-related genes ...