7. 小鼠肠道组织 肠道组织里,很多老师都会研究DC细胞,但是DC细胞的标志物CD11C,MHCII在肠道巨噬细胞中也会有表达,老师们在检测和数据分析圈门时要注意哦。 8. 小鼠皮肤组织 除了CD11B,F4/80marker外,可添加EPCAM,CD64,CD24等标...
Conventional APCs that express MHC class II (MHCII) and co‐stimulatory molecules include dendritic cells (DCs) and macrophages. Beyond these conventional APCs, immune stimulatory cells have been more recently shown to extend to a class of atypical APCs, composed of mast cells, basophils, and ...
Clinically Relevant Allergen Mixture Induces Robust Immune Response By Increasing CD11c+CD11b+MHCIIhiCD103int Lung Dendritic CellsClinically Relevant Allergen Mixture Induces Robust Immune Response By Increasing CD11c+CD11b+MHCIIhiCD103int Lung Dendritic CellsFemale Balb/c mice were sensitized intranasall...
结果:用 ADH-503 (GB1275)处理后,巨噬细胞的 MHCI、MHCII、CD80 和 CD86 表达水平更高,表明剩余巨噬细胞的抗原呈递特性有所改善。[1] 体内活性 方法:在大鼠和 C57/B6 小鼠中,给予ADH-503 (GB1275) (30,100mg / kg,口服)测试药代动力学 (PK) 和安全性。
CD11c+MHCII+CD64−DC (left) and relative frequencies of DC subsets (right) in the colonic LP ofRag1−/−Cre−orRag1−/−Cre+mice. Data are pooled from two independent experiments with a total of seven mice per group.eExpression of CD103 and CD11b by live CD11c+MHCII+DC ...
Cells were re-suspended in FACS buffer and incubated with Fc blocking antibody for 30 minutes, to prevent binding of nonspecific FcγRIII/II. Cells were then labeled with indicated antibodies (as a cocktail: Anti-CD11b, anti-CD11c, anti-CD45 anti-Gr1 anti-Siglec F and anti-MHCII), for...
Following CD11chighMHCII þ DC subsets were sorted and analyzed in a gene expression microarray: (1) CD103 þ CD11b À , (2) CD103 þ CD11b þ , and (3) CD103 À CD11b þ . (b) Transcript heat map of the B640 genes that are at least twofold differentially expressed ...
(TCR) capable of recognizing antigen when displayed on the surface of autologous cells, or any antigen-presenting matrix, together with one or more MHC molecules or, one or more non-classical MHC molecules. The term “T cells” as used herein denotes any T cells known in the art, for ...
Characterization of kidney CD45intCD11bintF4/80+MHCII+CX3CR1+Ly6C- “intermediate mononuclear phagocytic cells” Kidney immune cells play important roles in pathogenesis of many diseases, including ischemia-reperfusion injury (IRI) and transplant rejection. While studying murine kidney T cells, we se...
Therefore, we assessed the effects of a left unilateral vagotomy on total splenocytes and MHCII+/CD11+ B cells in the spleen 3 days after vagotomy. Results The results indicate that at 3 days after left unilateral vagotomy, there is a significant decrease in the overall number of spleno...