Cationic lipid-mediated nucleic acid delivery: beyond being cationic Chemistry and Physics of LipidsJournal2010,Chemistry and Physics of Lipids N. MadhusudhanaRao Lipoplexes with net positive charge and sizes less than a micron interact with thecell surface proteinsand sugars of the plasma membrane,...
membrane and allows the introduction of RNA to the cell due to the inability to distinguish the liposome from the cell membrane. Advantages of cationic lipid-mediated transfection include high efficiency, ability to transfect a wide range of cell types, reproducibility, low toxicity, and simplicity....
The present invention aims to provide a cationic lipid that can be used as a nucleic acid delivery carrier, a lipid membrane structure using a cationic lipid, a nucleic acid-introducing agent using a cationic lipid, and a method of achieving nucleic acid introduction by using a nucleic acid-...
DOTAP，132172-61-3，一种高效的阳离子脂质 (cationic lipid)，用于瞬时或者稳定转染 DNA (质粒、bacmids) 和修饰核酸 (反义寡核苷酸)，并且可以不使用辅助脂质。DOTAP（1,2-二油酰氧基-3-（三甲胺基）丙烷）的CAS号为132172-61-3，它是一种高效的阳离子脂质体试剂，具有广泛的用途。DOTAP主要用于体内外核酸...
Provided are a cationic lipid which facilitates the introduction of a nucleic acid into, for example, a cell or the like; a composition containing the cationic lipid and a nucleic acid; a method for introducing a nucleic acid into a cell by using a composition containing the cationic lipid ...
网络阳离子型脂质 网络释义 1. 阳离子型脂质 ...因治疗为主。这些非病毒性的基因载体,主要是利用阳离子型的高分子材料(cationic polymer)和低分子量的阳离子型脂质(catio… www.bioweb.com.tw|基于2个网页 例句
Introduction of a Disulfide Bond into a Cationic Lipid Enhances Transgene Expression of Plasmid DNA We have introduced a convenient method of synthesis for disulfide-containing cationic lipids. The lipid, 1,2-dioleoyl-sn-glycero-3-succinyl-2-hydroxyethyl ... F Tang,JA Hughes - 《Biochemical & Bi...
Cationic Lipid Transfection Viral Transfection DEAE-Dextran Transfection Calcium Phosphate Precipitation Cationic Polymer Transfection Other Physical Methods of Transfection What is cationic polymer transfection? Other cationic polymers used for gene delivery include ...
Cationic lipidCationic lipid 申请(专利)号: AU20150300046 申请日: 2015-08-06 专利号: AU2015300046A1 公开公告日: 2017-02-16 主分类号: C07C229/12 分类号: C07C229/12; A61K9/51; A61K31/7105; A61K31/713; A61K47/18; A61K48; A61P43; C12N15/113 申请权利人: TAKEDA PHARMACEUTICAL ...
Disclosed is a cationic lipid which is represented by formula (I) and makes it easier to introduce a nucleic acid into a cell. (In formula (I), R and R may be the same or different and each represents an alkenyl group or the like; X and X each represents a hydrogen atom, or alter...