aAntibacterial activity of the human host defence peptide LL-37 and selected synthetic cationic lipids against bacteria associated with oral and upper respiratory tract infections. 人的主人防御肽LL-37和选择的综合性负离子油脂的抗菌活动反对细菌与口头和上部呼吸道传染相关。[translate]...
The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery. Adv Drug Deliver Rev, 2016, 99: 129–137 Article CAS Google Scholar Adiseshaiah PP, Crist RM, Hook SS, et al. Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer....
Cationic lipids are used for delivering nucleic acids (lipoplexes) into cells for both therapeutic and biological applications. A better understanding of the identified key-steps, including endocytosis, endosomal escape and nuclear delivery is required for further developments to improve their efficacy. ...
核酸药物作为疾病治疗过程中一类新的生物治疗方式, 以核酸为靶标, 通过对蛋白翻译过程的调控, 实现疾病治疗, 在生物医学应用和治疗领域呈现出巨大的前景. 由于核酸类药物具有负电荷、高分子量和亲水性等特性, 因此需要载体来克服多种生物屏障, 以促进其在细胞内的递送. 基于阳离子材料的载体通过与核酸的静电相互作...
Amphiphilic cationic lipids are extensively studied because they may be used inthe composition of cationic liposomes as delivery agents of genetic material toeukaryotic cells (transfection), and as antitumor and antiviral agents. 阳离子脂质是非病毒类转基因载体阳离子脂质体的核心部分,其分子结构对阳离子脂...
Solid lipid nanoparticles (SLN) are nanoparticles generally made from solid lipids by high pressure homogenization. 固体脂质纳米粒通常是由固体脂质材料经高压乳匀法制备而成。 更多例句>> 5) solid lipid nanoparticle 固体脂质纳米粒 1. Preparation of stearic acid solid lipid nanoparticles containing podop...