Pathobiology of Human DiseaseCohen GM. Caspases: the executioners of apoptosis. Biochem J 1997;326(Pt. 1):1-16.G. M. Cohen, "Caspases: The Executioners of Apop- tosis," Journal of Biological Chemistry, Vol. 326, 1997, pp. 1-16.Cohen GM. Caspases: the executioners of apoptosis. ...
The central executioners of apoptosis: caspases or mitochondria? Apoptosis is a type of cell death whose morphological appearance relies on the activation of caspase-family cysteine proteases. Recently, it has become cle... Douglas Green a,Guido Kroemer b - 《Trends in Cell Biology》 被引量: 20...
Gamen S,Anel A,Pi?eiro A,Naval J.Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway. Cell Death and Differentiation . 1999Games S , Anel A , Pineiro A and Naval J ( 1998 ) Caspases are the main executioners of Fas-mediated ...
Apoptosis is a type of cell death whose morphological appearance relies on the activation of caspase-family cysteine proteases. Recently, it has become clear that inhibition of caspases does not always prevent irreversible loss of cellular function, although it does prevent the acquisition of apoptotic...
For example, caspases 8 and 3/7, commonly known as executioners of apoptosis, can promote microglia activation in the absence of cell death. K Caspases 8 and 3/7 are activated in microglia in the substantia nigra in Parkinson's disease subjects and the frontal cortex of Alzheimer's disease ...
The central executioners of apoptosis: caspases or mitochondria? Apoptosis is a type of cell death whose morphological appearance relies on the activation of caspase-family cysteine proteases. Recently, it has become cle... Douglas Green a,Guido Kroemer b - 《Trends in Cell Biology》 被引量: 20...
GM Cohen Caspases: the executioners of apoptosis. Biochem J., 326 (1997), pp. 1-16 CrossrefView in ScopusGoogle Scholar 38 V Cryns, J Yuan Proteases to die for. Genes Dev., 12 (1998), pp. 1551-1570 CrossrefView in ScopusGoogle Scholar 39 DW Nicholson, NA Thornberry Caspases: killer...
SJ Martin - 《Pathobiology of Human Disease》 被引量: 59发表: 2014年 Caspases: Executioners of Apoptosis Caspases (cysteine aspartate-specific proteases) coordinate the dismantling of the cell that takes place during apoptosis and activate the membrane changes that trigger recognition and removal of ...
We showed that caspases 8 and 3/7, commonly known to have executioner roles for apoptosis, can promote microglia activation in the absence of death. We found these caspases to be activated in microglia of PD and AD subjects. Inhibition of this signaling pathway hindered microglia activation and...
Caspases can be classed into three broad categories (Table 1): those which function as the proteolytic executioners of apoptosis ('killer' caspases; including -3 and -7), those which serve to activate the executioner caspases (initiator caspases; including -8 and -10), and those which have ...