4. Shen, S.Y. et al. (2018) Sensitive tumour detection andclassification using plasma cell-free DNA methylomes.Nature 563, 579–583 5. Laird, P.W. (2003) The power and the promise of DNA methylation markers. Nat. Rev. Cancer 3, 253–266 6. Issa, J.P. (2008) Cancer prevention: ...
基于DNA甲基化的生物标志物,可实现对mCRPC进行高特异性和敏感性的分类,并能够在不同治疗模式下区分有应答者和无应答者。重要的是,几个单独的标记基因具有独立于其他临床变量的放射学无进展生存的预后潜力。 参考文献: 1. Shen Shu Yi et al. Sensitive tumour detection and classification using plasma cell-free ...
Cancer Classification In subject area: Nursing and Health Professions Cancer classification refers to the systematic categorization of different types of lung cancer based on specific pathological characteristics, aiding in accurate diagnosis and treatment selection for patients....
The discovery and validation of the biological indicators (biomarkers) for human cancers are essential steps in the development of methods for accurate subtype classification and outcome prediction in clinic oncology. While genetics (SNP, LOH and mutation) and expression profiling (mRNA and protein) ...
With method of cluster analysis two cancer types are highlighted for which the hypothesis was confirmed stating that among the people affected by certain cancer types there are groups with principally different methylation pattern. 展开 关键词: cancer DNA methylation classification clustering DOI: ...
was determined post hoc using the prediction scores of the test set. The lowest threshold satisfying >95% specificity was chosen. Our final classification was based on the ensemble classifier; thus, samples detected as suspected cancer by the ensemble classifier further underwent TOO classification. ...
Brain Tumor Radiogenomic Classification of O6-Methylguanine-DNA Methyltransferase Promoter Methylation in Malignant Gliomas-Based Transfer Learning: Artificial Intelligence (AI) is the subject of a challenge and attention in the field of oncology and raises many promises for preventive diagnosis, but al.....
The automatic classification of X-ray detections is a necessary step in extracting astrophysical information from compiled catalogs of astrophysical source... Pérez-Díaz Víctor Samuel,Martínez-Galarza Juan Rafael,Caicedo Alexander,... - Monthly Notices of the Royal Astronomical Society 被引量: 0发...
Feature selection for DNA methylation based cancer classification. Bioinformatics 17, S157–S164 (2001). Article PubMed Google Scholar Miller, O. J., Schnedl, W., Allen, J. & Erlanger, B. F. 5-Methylcytosine localised in mammalian constitutive heterochromatin. Nature 251, 636–637 (1974)...
DNA methylation usually occurs at cytosine-guanine (CpG) dinucleotides, where DNA methyltransferases (DNMTs) catalyze the transfer of a methyl group to position 5 of a cytosine, generating 5-methylcytosine (5mC). DNMT1 maintains the patterns of DNA methylation after cell division using hemi-methylat...