Jones PA, Buckley JD. The role of DNA methylation in cancer. Adv Cancer Res .1990; 54:1-23.Jone PA. , Bucrley JD . The role of DN A met hylat ion in cancer. Adv. Cancer Res. 1990; 54: 1Jones P A, Buckley J D. The role of DNA methylation in cancer[ J]. Advances in ...
the roles of dna, rna and histone methylation in ageing and cancer ewa m. michalak abstract chromatin is a macromolecular complex predominantly comprising dna, histone proteins and rna. the methylation of chromatin components is highly conserved as it helps coordinate the regulation of gene expression...
The past few years have seen a wider acceptance of a role for DNA methylation in cancer. This can be attributed to three developments. First, the documentation of the over-representation of mutations at CpG dinucleotides has convincingly implicated DNA methylation in the generation of oncogenic poin...
Advances in Cancer ResearchJones PA, Buckley JD (1990) The role of DNA methylation in cancer. Adv Cancer Res 54: 1–23.Jones PA, Buckley JD. The role of DNA methylation in cancer. Adv Cancer Res. 1990; 54 :1–23. [ Pub... PA Jones - 《Advances in Cancer Research》 被引量: 457...
cancer, TXNIP expression is associated with different clinical outcomes, namely, improved survival in early-stage disease but poor survival in late-stage disease [23]. In this review, our focus is less on deciphering TXNIP’s prognostic impact but more on the role of TXNIP within the tumor ...
Cancer cells exhibit two opposing methylation abnormalities: genome-wide hypomethylation and gene promoter hypermethylation. Downregulation of E-cadherin (CDH1) plays a key role in the development of diffuse-type gastric cancer, and DNA methylation is a major cause of the gene's silencing. Hereditary...
Colorectal cancer is caused by the progressive accumulation of genetic and epigenetic events that lead to the malignant transformation of normal colonic epithelium. It is generally accepted that epigenetic alterations, particularly DNA hypermethylation, have an important role in the initiation and ...
Establishment of Two Data Mining Models of Lung Cancer Screening Based on Three Gene Promoter Methylations Combined with Telomere Damage: The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers. 2007; 23(1-2): 5–30. Google Scholar, Medline4. ... ...
Role of DNA Methylation in the Regulation of Cell Function: Autoimmunity, Aging and Cancer1,2 DNA methylation plays an essential role in maintaining cellular function, and changes in methylation patterns may contribute to the development of autoimmu... Bruce,C.,Richardson - 《Journal of Nutrition...
The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer CarcinogenesisKodach LL; Jacobs RJ; Heijmans J;.The role of EZH2 and DNA methylation in the silencing of the tumor suppressor RUbX3 in colorec- tal ... LL Kodach,RJ Jacobs,J ...