Understanding the relationships between aging mechanisms and aging conditions as a basis for identifying targets for interventions to extend healthy life span has been a long-standing goal of biomedical aging research. The identification of sufficiently valid, reliable, and accurate aging mechanistic ...
IgA nephropathy (IgAN) has become the leading cause of end-stage renal disease in young adults. Nevertheless, the current diagnosis exclusively relies on invasive renal biopsy, and specific treatment is deficient. Thus, our study aims to identify potenti
Understanding the relationships between aging mechanisms and aging conditions as a basis for identifying targets for interventions to extend healthy life span has been a long-standing goal of biomedical aging research. The identification of sufficiently valid, reliable, and accurate aging mechanistic ...
In 1,088 pregnant individuals, assessment of abnormal serum angiogenic factors is demonstrated to be noninferior to the standard clinical approach based on estimated fetal weight and Doppler percentiles for the identification of fetuses at a higher risk of neonatal acidosis or Cesarean delivery, thus ...
Statistical strategies and stochastic predictive models for the MARK-AGE data MARK-AGE aims at the identification of biomarkers of human aging capable of discriminating between the chronological age and the effective functional statu... Giampieri,Enrico,Remondini,... 被引量: 0发表: 0年 加载更多来源...
introduction of preventive measurements require objective assessment, i.e., the administration of biomarkers. Because of the complexity of skin aging, the exact definition of biomarkers is a major research challenge. In this article, we summarize the basic knowledge involving skin aging and its ...
The search for biomarkers that quantify biological aging (particularly ‘omic’-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the evaluation of interventions promoting healthy aging and longevity. However,...
Based on this progress, new diagnostic criteria for AD, MCI, and preclinical AD were proposed by National Institute of Aging (NIA) and Alzheimer's Association in August 2010. In these new criteria, progress in biomarker identification and amyloid imaging studies in the past 10 years have added...
The authors declare that they have no conflicts of interest. Rights and permissions Reprints and permissions About this article Cite this article Tarbit, E., Singh, I., Peart, J.N.et al.Biomarkers for the identification of cardiac fibroblast and myofibroblast cells.Heart Fail Rev24, 1–15 (...
Growing concern has arisen from the quasi-exponential increase in the numbers and quantities of man-made chemicals that presently are in current use, and their potential effects on human health, especially their delayed effects on degenerative diseases s