The search for biomarkers that quantify biological aging (particularly ‘omic’-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the evaluation of intervent
The expression levels of CEACAM1 and IL-1R1 exhibit a positive correlation with the percentage of neutrophils. Conclusion: Using machine learning techniques, our research identified four diagnostic biomarkers related to aging in peripheral blood, providing innovative approaches for the...
where a significant correlation between the scores and biomarkers of future diseases was observed7,14. Another study in Singapore with 4419 participants developed an MetS score to assess the performance of predicting diabetes in the follow-up15. However, both scores were derived based on a single,...
Flutamide can aggravate aging-related AD. Conclusion The results of this study suggest that cellular SRGs might play an important role in AD. PMSD14, PEBP1, ITPKB, and ATF7IP have the potential as specific biomarkers for the early diagnosis of AD. 展开 ...
Traditionally the diagnosis of Metabolic syndrome (MetS) is binary (present/absent). The goal of this work is to propose a sex-specific continuous score to measure the severity of MetS in Mexican adults using waist circumference and body mass index as ad
Identification of biomarkers correlated with diagnosis and prognosis of endometrial cancer using bioinformatics analysis. J Cell Biochem. 2020;121:4908–21. Article PubMed CAS Google Scholar Liu J, Feng M, Li S, Nie S, Wang H, Wu S, Qiu J, Zhang J, Cheng W. Identification of molecular ...
Flutamide can aggravate aging-related AD. Conclusion The results of this study suggest that cellular SRGs might play an important role in AD. PMSD14, PEBP1, ITPKB, and ATF7IP have the potential as specific biomarkers for the early diagnosis of AD.The Journal of Prevention of Alzheimer's ...
60 years of healthy aging: on definitions, biomarkers, scores and challenges. Ageing Res Rev. 2023;88:101934. Article PubMed Google Scholar Kowalski K, Rhodes R, Naylor PJ, Tuokko H, MacDonald S. Direct and indirect measurement of physical activity in older adults: a systematic review of...
The results of this study indicate that CDKN1A, VEGFA, MCL1, SNAI1, and MYC are key biomarkers that can be used to predict and prevent early aging-related OA. Lithium chloride, acetaminophen, curcumin, celecoxib, and resveratrol can be used for personalized treatment of aging-related OA....
The aim of this study was to evaluate the supportive role of molecular and structural biomarkers (CSF protein levels, FDG PET and MRI) in the early differential diagnosis of dementia in a large sample of patients with neurodegenerative dementia, and in determining the risk of disease progression ...