Diagnosis and clinical management of (beta)-Thalassemia minor in pregnancyM.A., ScharfP., BalanR.E., ScharfW., JanniR.E., Scharf
Dr. Neel recognized that the parents of children with thalassemia major had thalassemia minor with one beta thalassemia gene. When these parents had children, they had a 25% chance of having a thalassemia major child (with both genes for beta thalassemia), a 50% chance of having children with...
Beta thalassemia minor (BTM) is a hereditary disease caused by defective globin synthesis and it is frequently asymptomatic or only mildly anemic. Female sexual dysfunction affects 21–41% of women worldwide. In this study we aimed to investigate female sexual dysfunction in subjects with BTM. A...
The term thalassemia is derived from the Greek, thalassa (sea) and haima (blood). Beta-thalassemia includes three main forms: Thalassemia Major, variably referred to as "Cooley's Anemia" and "Mediterranean Anemia", Thalassemia Intermedia and Thalassemia Minor also called "beta-thalassemia carrier",...
The reason that the gene for beta thalassemia is relatively common, for example, among people of Italian and Greek origin is that parts of Italy and Greece were once full ofmalaria. The presence of thalassemia minor (like the sickle cell trait in Africa) afforded protection against malaria, an...
Alpha thalassemia trait (e.g. alpha thalassemia minor) (−α/−α) or (−−/αα) Normal to slightly increased Decreased Decreased Increased Increased Normal Normal to decreased Microcytosis, hypochromia, occasional targets No HbH disease (−−/−α) Decreased Decreased Decreased Decreas...
Beta thalassemia minor (BTM) is a hereditary disease caused by defective globin synthesis and it is frequently asymptomatic or only mildly anemic. Female sexual dysfunction affects 21–41% of women worldwide. In this study we aimed to investigate female sexual dysfunction in subjects with BTM. A...
Prevalence of Minor Beta Thalassemia (MBT) in Patients with Multiple Sclerosis (MS) in Southern Irandoi:10.1016/j.msard.2019.11.003Masood NomoviMaryam Sharifian DorcheAlireza NiksereshtMultiple Sclerosis and Related Disorders
Clinical management of thalassemia major con- sists in regular long-life red blood cell transfusions and iron chelation therapy to remove iron introduced in excess with transfusions. At present, the only definitive cure is bone marrow transplantation. Ther- apies under investigation are the ...
Beta-thalassemia is caused by the reduced (beta+) or absent (beta0) synthesis of the beta globin chains of the hemoglobin tetramer. Three clinical and hematological conditions of increasing severity are recognized, i.e., the beta-thalassemia carrier stat