Alpha thalassemia trait (e.g. alpha thalassemia minor) (−α/−α) or (−−/αα) Normal to slightly increased Decreased Decreased Increased Increased Normal Normal to decreased Microcytosis, hypochromia, occasional targets No HbH disease (−−/−α) Decreased Decreased Decreased Decreas...
BETA-ThalassemiaHYDROXYCHLOROQUINETEENAGERSDIAGNOSISDear Editor, A 9-year-old boy was consulted regarding an erythematous rash on the face that appeared 6 months ago. The patient, his mother and sister had concomitant 尾-thalassemia minor with a laboratory established anemia. Clinical examination revealed...
Hemoglobinopathies and Thalassemias Amer Wahed MD, Amitava Dasgupta PhD, DABCC, in Hematology and Coagulation, 2015 4.2 Hemoglobin Structure and Synthesis Hemoglobin, the oxygen-carrying pigment of erythrocytes, consists of a heme portion (iron-containing chelate) and four globin chains. Six distinct...