(2012). Is blood transfusion therapy the ideal treatment for β- thalassemia intermedia? K Constantinou - 《Open Journal of Hematology》 被引量: 2发表: 2012年 How I Treat... GI: gastrointestinal; IOL: iron overload; TD: transfusion dependent; BTM: beta-thalassemia major;DFO: deferoxamine; ...
The purpose of this article is to set forth our approach to diagnosing and managing the thalassemias, including 尾-thalassemia intermedia and 尾-thalassemia major. The article begins by briefly describing recent advances in our understanding of the pathophysiology of thalassemia. In the discussion on...
Exjade is also used to treat chronic iron overload syndrome caused by a genetic blood disorder (non-transfusion-dependent thalassemia) in adults and children who are at least 10 years old.WarningsYou should not use Exjade if you have severe kidney or liver disease, advanced cancer, a blood ...
focusing on Sickle Cell and Thalassemia. These platforms facilitate the seamless sharing of data and insights across borders, fostering a collective approach to understanding and combating rare diseases. By creating
However, in sickle cell disease and beta thalassemia, people have faulty versions of the adult gene. Casgevy reverses the switch to adult hemoglobin so that patients can continue using their fetal hemoglobin gene instead. One form of inherited blindness may be among the next disorders treated ...
In southern European countries, such as Greece and Italy, screening programs for hemoglobinopathies, such as b-thalassemia, have been implemented decades ago.94 The genetic screening programs mentioned above either aim to provide people with information that enables them to make informed reproductive ...
Stunning advances in gene research and data mining will predict diseases and devise treatments tailored to each of us.
People with thalassemia have varying degrees of anemia. In one of the more severe cases, such asbeta-thalassemiamajor, there is an inability to maintain hemoglobin at levels greater than 6.5 g/dL [61]. While some people with the disorder require regular blood transfusion, others require sporadic...
In this article, we discuss management of hypoxia based on three different cases; sickle cell disease, beta- thalassemia and hereditary spherocytosis. These cases are used to review the current understanding of the disease pathophysiology, demonstrate the importance of a thorough clinical history and ...
Yongrong LaiZhonghua Xue Ye Xue Za ZhiRachmilewitz EA, Giardina PJ. How I treat thalassemia. Blood. 2011;118(13):3479- 3488.Rachmilewitz EA, Giardina PJ. How I treat thalassemia. Blood. 2011; 118(13): 3479-3488.Rachmilewitz EA, Giardina PJ. How I treat thalassemia. Blood. 2011;118(...