Treatment of thalassemia major includes regular RBC transfusions, iron chelation and management of secondary complications of iron overload. In some circumstances, spleen removal may be required. Bone marrow transplantation remains the only definitive cure currently available. Individuals with thalassemia ...
Dr. Neel recognized that the parents of children with thalassemia major had thalassemia minor with one beta thalassemia gene. When these parents had children, they had a 25% chance of having a thalassemia major child (with both genes for beta thalassemia), a 50% chance of having children with...
Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is ...
spinal cord compression syndromethalassemia majorExtramedullary hematopoiesis is a normal compensatory reaction that can affect the epidural space, leading to spinal cord compression syndrome. MRI is the imaging method of choice for diagnosis and monitoring. Treatment is still controversial....
Deferiprone in the treatment of transfusion-dependent thalassemia: a review and perspective. Ther Clin Risk Manag 2007; 3: 795–805. CAS PubMed PubMed Central Google Scholar Neufeld EJ . Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, ...
Although the possibility of asymptomatic course for COVID infection in splenectomized thalassemia beta major patients is present, screening them for COVID is important as the progression is still not clear. Although the possibility of asymptomatic course for COVID infection in splenectomized ...
—Thyroid dysfunction is one of the most frequently reported complications of chronic blood transfusion therapy in patients with beta-thalassemia major (BTM). However, the occurrence of thyroid dysfunction and its possible association with iron overload in BTM patients is still under debate. Therefore...
1791 – A case of psychosis in a patient affected by beta thalassemia major: a genetic link? 来自 EBSCO 喜欢 0 阅读量: 21 作者:Ranieri, R.,Demartini, B.,Mormandi, G.,Scarone, S.摘要: A 35-year-old man affected by betathalessemia major was treated at the age of 10 years old by...
The effect of repeated transfusions on active cytomegalovirus infection, in the presence of IgM, in patients with thalassemia major in Iran. Payavard Salamat. 2007;1(1):8-16. eng %@ 1735-8132 %[ 2007.Choobineh H. Serological Evaluation of Major Beta Thalassemia Patients below15 for ...
Individuals with thalassemia major have severe anemia and hepatosplenomegaly; they usually come to medical attention within the first two years of life. Without treatment, affected children have severe failure to thrive and shortened life expectancy. Treatment with a regular transfusion program and ...