Bax ihibitor-1 (BI-1) has been characterized as an inhibitor of Bax-induced cell death in plants and various mammalian cell systems. To explore the function of BI-1 in neurons, we overexpressed BI-1 tagged to HA or GFP in rat nigral CSM14.1 and human SH-SY5Y neuroblastoma cells. ...
BI-1也被称为含跨膜Bax抑制因子的基序6(transmembrane bax inhibitor motif containing 6,TMBIM6),是一个含6~7个跨膜区的细胞内膜蛋白, 主要定位于细胞内膜, 如粗面内质网、线粒体等[10]。 关于BI-1的功能,目前研究已证明BI-1与...
该Bax inhibitor-1 (OsBI-1) 抗体(Bax inhibitor-1 (OsBI-1) antibody)产品的背景资料详情,请查看Covalab提供的产品说明书。 其他 Covalab位于法国,自1995年公司成立以来,在抗体开发和生产方面拥有卓越的经验。Covalab提供超过15000种产品,包括抗体和试剂盒。拥有多种针对流行和罕见靶标的一抗,涉及多种应用领域,如...
baxinhibitor1(bi1),也称为跨膜bax inhibitor motif containing 6 (tmbim6),可通过与很多蛋白相互作用发挥其抗凋亡活性,比如n端可与bcl2和bclxl蛋白相互作用。尽管bi1对于抑制bax活性发挥重要作用,也有报道证明bi1具有一定的神经保护作用,对于线粒体功能障碍及自噬的发生也具有重要的影响,但bi1对于神经退行性疾病发...
BAX (BCL2-associated X protein) inhibitor-1 (BI-1) is a Ca(2+) leak channel also implicated in the response against protein misfolding, thereby connecting the Ca(2+) store and protein-folding functions of the ER. We found that BI-1-deficient mice suffer from leukopenia and erythrocytosis...
中国农业大学 硕士学位论文 番茄Baxinhibitor-1(LeBI-1)基因的遗传转化及其鉴定 姓名:*** 申请学位级别:硕士 专业:食品科学 指导教师:**芹 20070501 中国农业大学硕士学位论文摘要 摘要 细胞程序性死亡(PCD),是多细胞生物清除不必要的、多余的、受感染的或损坏细胞自主 性死亡过程,在动植物正常生长发育和胁迫条件...
BI-1 | Bax inhibitor-1 (100 μl) 英文名称: BI-1 | Bax inhibitor-1 (100 μl) 总访问: 325 国产/进口: 进口 半年访问: 5 产地/品牌: agrisera 产品类别: 植物试剂 规格: AS122221-100 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
Bax Inhibitor-1 (BI-1) is an evolutionary conserved endoplasmic reticulum (ER)-located protein that protects against ER stress-induced apoptosis.1This function has been closely related to its ability to permeate Ca2+from the ER2and to lower the steady-state [Ca2+]ER.3BI-1 may function as ...
Background Bax inhibitor-1 (BI-1) is an evolutionary conserved endoplasmic reticulum protein that, when overexpressed in mammalian cells, suppresses the apoptosis induced by Bax, a pro-apoptotic member of the Bcl-2 family. The aims of this study were: (1) to clarify the role of intrinsic an...
The ubiquitous Bax inhibitor-1 (BI-1) is a common cell death suppressor in eukaryotes that has provided a potential portal to this cell death core. In this review, we will update the current status of our understanding on the function and activities of this intriguing protein. Genetic, ...