baxinhibitor1(bi1),也称为跨膜bax inhibitor motif containing 6 (tmbim6),可通过与很多蛋白相互作用发挥其抗凋亡活性,比如n端可与bcl2和bclxl蛋白相互作用。尽管bi1对于抑制bax活性发挥重要作用,也有报道证明bi1具有一定的神经保护作用,对于线粒体功能障碍及自噬的发生也具有重要的影响,但bi1对于神经退行性疾病发...
BI-1也被称为含跨膜Bax抑制因子的基序6(transmembrane bax inhibitor motif containing 6,TMBIM6),是一个含6~7个跨膜区的细胞内膜蛋白, 主要定位于细胞内膜, 如粗面内质网、线粒体等[10]。 关于BI-1的功能,目前研究已证明BI-1与...
Emerging data from our recent study now provide compelling evidence that a conserved cell death suppressor, BAX inhibitor-1 (BI-1), plays a pivotal role as a survival factor against endoplasmic reticulum stress-mediated programmed cell death (PCD) that likely acts in parallel to the UPR pathway...
BI-1 | Bax inhibitor-1 (200 μl) 英文名称: BI-1 | Bax inhibitor-1 (200 μl) 总访问: 290 国产/进口: 进口 半年访问: 7 产地/品牌: agrisera 产品类别: 植物试剂 规格: AS122221 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
关键词:Bax抑制因子1;视神经萎缩蛋白1;血管钙化;细胞骨型分化;细胞凋亡 Abstract:Objective To investigate the effects of Bax inhibitor 1 (BI- 1) and optic atrophy protein 1 (OPA1) on vascular calcification (VC). Methods Mouse models of VC were established in ApoE-deficient (ApoE-/-) diabetic ...
the bax inhibitor mrbi-1 regulates heat tolerance, apoptotic-like cell death, and virulence in metarhizium robertsii:bax抑制剂mrbi-1调节热耐受,凋亡样细胞死亡,并在robertsii绿僵菌毒力 热度: 金属硫蛋白在抑制糖尿病心肌病中内质网应激介导心肌细胞凋亡中作用的研究 ...
转番茄Bax inhibitor-1基因烟草悬浮细胞系的建立
The ubiquitous Bax inhibitor-1 (BI-1) is a common cell death suppressor in eukaryotes that has provided a potential portal to this cell death core. In this review, we will update the current status of our understanding on the function and activities of this intriguing protein. Genetic, ...
Bax inhibitor 1 (BI-1) was originally discovered as an inhibitor of Bax-induced apoptosis; this review highlights the fundamental importance of BI-1 in a wider context, including in tissue homeostasis and as a regulator of cellular stress. BI-1 has been shown to interact with a broad range...
Bax inhibitor-1Oxidative stressSphingolipidVery-long-chain fatty acidBax inhibitor-1 (BI-1) is a widely conserved cell death regulator that confers resistance to environmental stress in plants. Previous studies suggest that Arabidopsis thalianaBI-1 (AtBI-1) modifies......