关键词:Bax抑制因子1;视神经萎缩蛋白1;血管钙化;细胞骨型分化;细胞凋亡 Abstract:Objective To investigate the effects of Bax inhibitor 1 (BI- 1) and optic atrophy protein 1 (OPA1) on vascular calcification (VC). Methods Mouse models of VC were established in ApoE-deficient (ApoE-/-) diabetic ...
Keywords: idiopathic pulmonary fibrosis; BI-1; epithelial—mesenchymal transition; ER stress; lysosome; V-ATPase glycosylation Abbreviations: ER, endoplasmic reticulum; IPF, idiopathic pulmonary fibrosis; BI-1, Bax inhibitor-1; TGF, transforming growth factor; ECM, extracellular matrix; a-SMA, a-...
Bax inhibitor-1Oxidative stressSphingolipidVery-long-chain fatty acidBax inhibitor-1 (BI-1) is a widely conserved cell death regulator that confers resistance to environmental stress in plants. Previous studies suggest that Arabidopsis thalianaBI-1 (AtBI-1) modifies......
BI-1 | Bax inhibitor-1 (200 μl) 英文名称: BI-1 | Bax inhibitor-1 (200 μl) 总访问: 294 国产/进口: 进口 半年访问: 11 产地/品牌: agrisera 产品类别: 植物试剂 规格: AS122221 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
Bax Inhibitor-1 (BI-1) is an evolutionary conserved endoplasmic reticulum (ER)-located protein that protects against ER stress-induced apoptosis.1This function has been closely related to its ability to permeate Ca2+from the ER2and to lower the steady-state [Ca2+]ER.3BI-1 may function as ...
Bax inhibitor-1 Mouse embryonic stem cell Mitogen-activated protein kinase Neuronal differentiation 1. Introduction Embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of blastocysts and are characterized by their ability to proliferate extensively and differentiate into various...
The overexpression of Bax inhibitor-1 (BI-1) in prostate carcinoma and prostate cancer cell lines was confirmed by using Northern blot and Western blot analyses. Quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) on intact RNAs from 17 paired laser-captured micro...
Mol Cell 1998; 1: 337–346. Article CAS Google Scholar Kawai M, Pan L, Reed JC, Uchimiya H . Evolutionally conserved plant homologue of the Bax inhibitor-1 (BI-1) gene capable of suppressing Bax-induced cell death in yeast. FEBS Lett 1999; 464: 143–147. Article CAS Google ...
OPEN SUBJECT AREAS: CHEMOTHERAPY CALCIUM SIGNALLING Received 5 November 2013 Accepted 20 May 2014 Published 5 June 2014 Bax Inhibitor-1-Mediated Inhibition of Mitochondrial Ca21 Intake Regulates Mitochondrial Permeability Transition Pore Opening and Cell Death Geum-Hwa Lee1, Hwa-Young Lee1, Bo Li1,...
The present invention provides substantially purified nucleic acid molecules encoding Bax inhibitor protein-1 (BI-1; SEQ ID NO: 1) or Bax inhibitor protein-2 (BI-2; SEQ ID NO: 4), nucleic acid molecules complementary thereto (SEQ ID NO: 2 and SEQ ID NO: 5, respectively), portions of ...