Dawson D J,Brock P J. Base hydrolysis of pendant amide polymers[P].US 4393174 1983.US4393174 * Nov 9, 1981 Jul 12, 1983 Dynapol Base hydrolysis of pendant amide polymersUS4393174 * 1981年11月9日 1983年7月12日 Dynapol Base hydrolysis of pendant amide polymers...
ChemInform Abstract: STEREOELECTRONIC CONTROL IN ACID AND BASE CATALYSIS OF AMIDE HYDROLYSIS. A THEORETICAL STUDY J.-M.,LEHN,G.,... - 《Chemischer Informationsdienst》 被引量: 83发表: 1980年 Theoretical mechanistic study of TangPhos-catalyzed asymmetric γ addition of thiols to allenoates TangPhos-...
Base-catalyzed hydrolysis proceeds either through an intermolecular SN2 reaction to hydroxy-substituted derivatives or (in a few cases) through amide cleavage, while both amide and ether group cleavages are observed under acidic conditions. Our results reveal that subtle differences in chloroacetamide ...
Therefore, N-Mannich bases prodrugs could be an excellent strategy to enhance the delivery of the active compound due to the enhancement in water solubility as well as enhancement in lipophilicity. The rate of hydrolysis of N-Mannich bases is the same in plasma and in buffer since its ...
In this model, an enzymatic lysine attacks C4 of uridine to form a Schiff base RNA–protein conjugate. Sequenced RT-PCR products from the fern Ceratopteris richardii indicate U-to-C base edits do not preserve proteinaceous crosslinks in planta. Hydrolysis of a protonated Schiff base conjugate ...
Is bicarbonate of soda an acid or base? Write a base (NaOH) hydrolysis reaction for (a) Hexanoic acid, (b) Methyl hexanoate, and (c) N-methyl Butanamide. When titrating acids and bases (Weak or strong), how do you determine whether you use H2O o...
Thioacetamide and N-methylpropionamide, both as amide analogues, were shown to inhibit the biosynthesis of acetamidase. Similarly, the organic acids, products of the hydrolysis reaction, showed a strong repression action on the biosynthesis of the enzyme. 展开 ...
A simple, efficient procedure for the conversion of phenylhydrazine to 1-alkyl-1-phenylhydrazines via base-promoted hydrolysis of 1-alkyl-3-amino-4,5-dihydro-1-phenyl-1H-pyrazolium iodides (2) is described. N1, N1-disubstituted hydrazones of trans-cinnamamide and acrylamide are obtained by ...
Evidence that separation of a nonbonded complex can be rate determining. J Am Chem Soc;104:2891-2897.Kluger, R.; Lam, C.-H., Carboxylic Acid Participation in Amide Hydrolysis. External General Base Catalysis and General Acid Catalysis in Reactions of Norborneneyanilic Acids. Journal of the ...
The properties of the transition state for serine protease-catalyzed hydrolysis of an amide bond were determined for a series of subtilisin variants from B... RR Bott,G Chan,B Domingo,... - 《Biochemistry》 被引量: 27发表: 2003年 Mechanism of hydrolysis of a thiazolium ion: General acid-...