The twisted amides are stabilized by the rigid cavity of the cage and are thus up to 14 times more reactive toward hydrolysis under basic conditions.doi:10.1016/j.chempr.2020.05.009You-Quan ZouIlma JahoviJonathan R. NitschkeChem
Simple amides ordinarily are prepared by reaction of acids or acid halides with ammonia or amines. They can also be produced by the reaction of water with nitriles. The characteristic reaction of covalent amides is hydrolysis (a chemical reaction with water), by which they are converted to ...
Chemoselective enzymatic hydrolysis of aliphatic and alicyclic nitriles Mild and selective hydrolysis of aliphatic and alicyclic nitriles leading to carboxylic acids and amides was achieved under neutral conditions by an immobi... AD Raadt,N Klempier,K Faber,... - 《Journal of the Chemical Socie...
ZrO2 was demonstrated to be applicable to the hydrolysis of amide bonds: dipeptides with acidic or basic side chain into amino acids; small organic amides into both amines and carboxylic acids with their equivalent amounts; and nylon 6 into 蔚-caprolactam and 蔚-aminocaproic acid.Catalysis Science...
ChemInform Abstract: MICELLAR CATALYSIS OF THE BASIC HYDROLYSIS OF AMIDES. 4. SUBSTITUTED N,N‐DIPHENYL BENZAMIDESsolvolysis, hydrolysisDie basische Hydrolyse der Amide (I)-(III) wird in Gegenwart von Cetyltrimethylammoniumchlorid untersucht.doi:10.1002/chin.198202098...
and the large number of functional groups that can undergo hydrolysis. Hydrolysis generally occurs via an acid- or base-catalyzed mechanism but can also occur under neutral conditions where water can act as abase. The carbonyl function of esters,lactones,amides,lactams,carbamates, andimidesare susce...
In the basis pH region, furosemide hydrolysis is extremely slow. Using the Arrhenius parameters obtained from the studies, furosemide would have a half-life of 178 min under physiological conditions in the stomach of pH 1.0 and temperature of 37.degree. C....
Chemischer InformationsdienstLinda, P., et al., Hydrolysis of Amides - Kinetics and Mechanism of the Basic Hydrolysis of N-Acylpyrroles, N-Acylindoles and N-Acylcarbazoles. Journal of Heterocyclic Chemistry, 1983. 20(1): p. 247-248.
Under a Creative Commons license open accessHighlights Abstract Calcium binding to peptides formed by hydrolysis of whey proteins during digestion is important for calcium uptake in the intestines and affects the antioxidant function of the peptides. For the two dipeptides, Gly-Tyr and Tyr-Gly, pot...
Under a Creative Commons license open accessThe biological activities of Rho family GTPases are controlled by their guanine nucleotide binding states in cells. Here we have investigated the role of Mg2+ cofactor in the guanine nucleotide binding and hydrolysis processes of the Rho family members, ...