B7-H3 expression was quantified by RNA sequencing and by IHC on pediatric PDX microarrays. We tested the safety and efficacy of m276-SL-PBD in two stages. Randomized trials of m276-SL-PBD of 0.5 mg/kg on days 1...
3 Pinho, S. S. & Reis, C. A. Glycosylation in cancer: mechanisms and clinical implications. Nature reviews. Cancer 15, 540-555, doi:10.1038/nrc3982 (2015).4 Liu, C. et al. B7-H3 expression in ductal and lobular breast cancer and its association with IL-10. Molecular medicine repor...
[5]Pan-cancer associations of B7-H3 (CD276) transcriptional expression across human malignancies.. JCO 41, 2624-2624(2023).DOI:10.1200/JCO.2023.41.16_suppl.2624 [6]百济神州实体瘤管线官网beigenemedical.com/pipe [7]A novel B7-H3 x CD3 bispecific T-cell engager for the treatment of B7-H3...
[6] Inamura K , Amori G , Yuasa T , et al. Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma[J]. Cancer Management and Research, 2019, Volume 11:7021-7030. [7] Majzner R G , Theruvath J L , Nellan A ...
[6] Inamura K , Amori G , Yuasa T , et al. Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma[J]. Cancer Management and Research, 2019, Volume 11:7021-7030. ...
免疫检查点B7-H3表达与结肠癌的预后关系(A three-phase trans-ethnic study reveals B7-H3 expression is a significant and independent biomarker associated with colon cancer overall survival) 内容亮点 B7-H3基因表达与肠癌预后的统计...
carcinoma.B7-H3 expression in gastric carcinoma samples wasnot related with the patients'age,sex,lymph nodemetastasis,and tumor size(P>0.05),but with thesurvival time,infiltration depth of tumor and tissue type.CONCLUSION:Detection of B7-H3 expression in gastriccarcinoma tissue is beneficial...
免疫检查点B7-H3表达与结肠癌的预后关系(A three-phase trans-ethnic study reveals B7-H3 expression is a significant and independent biomarker associated with colon cancer overall survival) 内容亮点 B7-H3基因表达与肠癌预后的统计学关联在多个既往研究中结论并不一致。本研究利用TCGA数据库(n=433)、GEO数据...
Recently, the aberrant expression of B7-H3 has been described in various malignancies, and significantly correlated with poor prognosis and cancer progression. Therefore, B7-H3 is considered as an early diagnostic and prognostic marker and therapeutic target for tumors, but the specific molecular ...
[10] Veenstra R G, Flynn R, Kreymborg K,et al. B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality [J]. Blood, 2015, 125(21): 3335-3346. [11] Hofmeyer K A, Ray A, Zang X. The contrasting role of B7-H3 [J]. Procee...