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While autophagy is intimately linked to health, the intricate relationship among autophagy, aging and disease remains unclear. This Review examines several emerging features of autophagy and postulates how they may be linked to aging as well as to the development and progression of disease. In ...
Thus, the detection and characterization of the autophagy regulatory network may open new avenues of research in many therapeutic approaches.doi:10.1097/MOG.0b013e32833ae2edR.A. GottliebAnticancer ResearchGottlieb RA, Carreira RS. Autophagy in health and disease. 5. Mitophagy as a way of life. ...
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Autophagy in human health and disease In eukaryotes, autophagy represents a highly evolutionary conserved process, through which macromolecules and cytoplasmic material are degraded into lysoso... AMK Choi,SW Ryter,L Beth - 《New England Journal of Medicine》 被引量: 0发表: 2018年 Autophagy: princ...
Autophagy in health and disease. 1. Regulation and significance of autophagy: an overview. Mehrpour M,Esclatine A,Beau I, et al.Autophagy in health and disease.1.Regulation and significance of autophagy: an overview. American Journal of ... Mehrpour,Maryam,Esciatine,... - 《American Journa...
Aiming to expand the therapeutic potential of autophagy, many researchers focus on developing new drugs or treatment strategies for Parkinson's disease, rheumatic diseases and oncogenesis by controlling cell fate via regulating molecular pathways. This series aims to highlight essential molecular and ...
Choi AM, Ryter SW, Levine B (2013) Autophagy in human health and disease. N Engl J Med 368:651–662. https://doi.org/10.1056/NEJMra1205406 Article CAS Google Scholar Chung Y-H et al (2012) Microtubule-associated protein light chain 3 regulates Cdc42-dependent actin ring formation in ...
material); the connections between autophagy and various aspects of human health and disease including, cancer, neurodegeneration, aging, diabetes, myopathies and heart disease; and we are interested in all experimental systems, from yeast to human. Suggestions for appropriate specialized topics are ...
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