Autophagy in cardiovascular biology . J Clin Invest 2015; 125 :55-64; PMID:25654551; http://dx.doi.org/10.1172/JCI73943 [ Cross Ref ]Lavandero S, Chiong M, Rothermel B, Hill J. Autophagy in cardiovascular biology . J Clin Invest 2015; 125 : 55–64....
Autophagy in cardiovascular biology. Cardiovascular disease is the leading cause of death worldwide. As such, there is great interest in identifying novel mechanisms that govern the cardiovascular response to disease-related stress. First described in failing hearts, autoph... S Lavandero,M Chiong,B...
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Despite recent scientific and technological advances, cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Autophagy, an evolutionarily ancient response to cellular stress, has been implicated in the pathogenesis of a wide range of heart pathologies. However, the precise ...
An indication of the complexity of the autophagic process is given by the number (at least 40) specialised proteins involved. A large number of research projects, and their ensuing publications, have been devoted to the genetics, cell biology, andof the process, particularly in what refers to ...
Revelation of connection with autophagy in cardiomyocytes could give a new dimension to studies involving HO-1. The precise role of autophagy in cardiovascular system has always elicit controversy; there are evidence to support its role as a saviour [21] and also as a killer [22]. Our results...
Autophagy, an evolutionarily conserved process for the bulk degradation of cytoplasmic components, serves as a cell survival mechanism in starving cells1,2. Although altered autophagy has been observed in various heart diseases, including cardiac hypertr