Autophagy - animal Autophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily conserved among eukaryotes and exquisitely regulated. This progress initiates with production of...
Autophagy in post-embryonic animal development Autophagy participates in post-embryonic animal develop- ment where it can mediate gene silencing, cell-fate deter- mination and promote survival in stressful environments. In fact, multiple animals require autophagy either to survive periods of developmental...
Through experiments that focus on animal development, fundamental mechanisms that control autophagy and that contribute to disease were elucidated. Studies in embryos revealed specific autophagy molecules that mediate the removal of paternally derived mitochondria, and identified autophagy components that clear...
Macroautophagy core proteins were found in yeast and later in animal models -mice, Drosophila, C. elegans and zebrafish- including ATG13, ATG9, ATG14, ATG10, ATG4, ATG9 and LC3B. Read the blog!
Through experiments that focus on animal development, fundamental mechanisms that control autophagy and that contribute to disease were elucidated. Studies in embryos revealed specific autophagy molecules that mediate the removal of paternally derived mitochondria, and identified autophagy components that clear...
Macroautophagy core proteins were found in yeast and later in animal models -mice, Drosophila, C. elegans and zebrafish- including ATG13, ATG9, ATG14, ATG10, ATG4, ATG9 and LC3B. Read the blog!
A conditioned autophagy-deficient animal and a disease model animal. Namely, a knockout animal in which the function of a gene causative of autophagy is entirely or partly impaired depending on Cre recombinase; a disease model animal comprising a knockout animal in which the function of a gene...
来源期刊 蛋白质与细胞 研究点推荐 Autophagy Animal genes identification mTOR signaling reactivation 引用走势 2016 被引量:5 站内活动 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心,砥砺前行。了解更多...
In this review, we aimed elucidate the relationship between autism and autophagy mechanism in well-known autism relevant animal models. Autophagy is a cell-protective mechanism that allows cell survival in low nutrient conditions, often through the degradation of aging and damaged proteins and ...
remodeling.Autophagy is a process that cells digest their cellular contents to provide energy and nutrients to maintain homeostasis.Until now,whether autophagy persists during mitosis is still debated.In most dividing animal cells,the whole cell cycle can be divided into about 20 h of interphase and...