This article is cited by Astrocyte-derived dominance winning reverses chronic stress-induced depressive behaviors Kyungchul Noh Junyoung Oh Sung Joong Lee Molecular Brain(2024) Molecular Psychiatry (Mol Psychiatry)ISSN1476-5578(online)ISSN1359-4184(print)...
The greatest changes in a marker of the astrocyte cytoskeleton (glial fibrillary acidic protein, GFAP ) were observed in the hippocampus of alcoholized animals, where the GFAP level was by 72% lower with respect to the control values. In this cerebral region, the content of the neurofilament ...
Damage to neuronal or astrocyte structures could be some of the contributing factors for these illnesses. In this study, we have shown that METH damages neurite-like processors (Fig. 3D). These data suggest that this damage could be a contributing factor to these illnesses. It is disheartening...
These cytoprotective responses may facilitate astrocyte survival and the development of reactive gliosis in the face of concomitant neuronal degeneration. CSH-treated astrocytes may serve as a model for the (dys)regulation of neuroglial MnSOD and other antioxidant enzymes in the aging and ...
To explore this point, we built up a PQ-induced model in cultural U118 astrocyte. Since the granin family is considered as a master regulator of cargo sorting and large dense core vesicles (LDCVs) biogenesis in the regulated secretory pathway of nervous and neuroendocrine cells, the current ...
Glutamate-mediated astrocyte–neuron signalling. Nat. Cell Biol. 1994, 369, 744–747. [Google Scholar] [CrossRef] [PubMed] Nedergaard, M. Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science 1994, 263, 1768–1771. [Google Scholar] [CrossRef] [PubMed] ...
(IBA1) and astrocyte glial fibrillary acidic protein (GFAP) integrated density, number and morphological transformation in pain-related brain regions were determined. CRS induced 15–20% mechanical hyperalgesia after 2 weeks in WT mice in both sexes, which was significantly reduced in female but ...
Dual cellular tropism of PHP.eB viruses, observed using different doses and different delivery protocols (local vs. systemic), suggests that the usage of AAV5 is more reliable for astrocyte labeling and that intrahippocampal injection is more suitable than systemic injection for the preferential ...
However, the knowledge on astrocyte development is mainly obtained from rodents. Much remains a Olig2PC-Astro VS NPC-Astro b 104 NPC-Astro Olig2PC-Astro 103 1,377 12,570 911 102 101 c R2=0.9233 102 103 104 NPC-Astro 105 d BDNF BMP1 BMP2 BMP4 BMP8B NOG TGFB2 TGFB3 TGFBRAP1 ...
Our findings suggest a previously undescribed neuronal exosomal miR-mediated genetic regulation of astrocyte functions, potentially opening a new frontier in understanding CNS intercellular communication.doi:10.1038/s41467-019-11534-wYuqin MenJulia Yelick...