Astrocyte regulation of synaptic behavior. Annu. Rev. Cell Dev. Biol. 30, 439–463 (2014). Article CAS PubMed Google Scholar Filosa, J.A. et al. Local potassium signaling couples neuronal activity to vasodilation in the brain. Nat Neurosci. 9, 1397–1403 (2006). Article CAS PubMed ...
(2011). A tale of two stories: astrocyte regulation of synaptic depression and facilitation. PLoS Comput. Biol., 7(12):e1002293.DE PITTA M., VOLMAN V., BERRY H. & BEN-JACOB E. (2011). A Tale of Two Stories: Astrocyte Regulation of Synaptic Depression and Facilitation. PLoS ...
Hippocampal astrocytes modulate anxiety-like behavior Astrocytes affect animal behaviors by regulating the tripartite synapse. Here, the authors show that hippocampal astrocytes modulate mouse anxiety-like behavior by regulating synaptic homeostasis of dentate gyrus granule cells via ATP release. Woo-Hyun ...
Evidence from the literature indicates a myriad of changes observed in astrocytes from both human postmortem studies as well as preclinical animal models, including changes in expression of glial fibrillary protein, as well as changes in astrocyte morphology and astrocyte-mediated regulation of synaptic ...
and the functional consequences of reactivity are unclear [7,9,47,67]. In Alzheimer’s disease (AD), the most frequent neurodegenerative disease (ND) characterized by amyloid and Tau deposition in the brain, as well as memory loss and synaptic alterations, the role of reactive astrocytes is ...
Paracrine factors from the astrocytes also contribute to regulation of blood flow [9]. One of the major regulatory functions of astrocytes in the NVU occurs during inflammation. Astrocytes, through regulation of matrix metalloproteinase, control breakdown of the basement membrane that allows movement of...
The role of light signaling on astrocytic morphological plasticity in the adult male rat suprachiasmatic nucleus The SCN then relays this information to the brain and the rest of the body through synaptic signaling and indirectly through circadian regulation of hormonal signaling. The SCN is unique in...
Regulation of astrocyte functions in multiple sclerosis.Cold Spring Harb. Perspect. Med. 2019; 9: a029009Crossref PubMed Scopus (15) Google Scholar], microbial infections [19.Drogemuller K. et al.Astrocyte gp130 expression is critical for the control of Toxoplasma encephalitis.J. Immunol. 2008...
One of the first behaviors that is suspected to be under astrocyte control is circadian rhythm, in part because the earliest understanding of astrocytes suggested that they regulate homeostatic control. The mammalian circadian system is derived from oscillatory regulation of transcription factors. It is...
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