Perez-Alvarez A, Araque A: Astrocyte-neuron interaction at tripartite synapses. Curr Drug Targets 2013, 14 (11):1220–1224.Perez-Alvarez, A., and Araque, A. (2013). Astrocyte-neuron interaction at tripartite synapses. Curr. Drug Targets 14, 1220-1224. doi: 10.2174/13894501113149990203...
Dringen, R., Gutterer, J.M., Hirrlinger, J.: Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur. J. Biochem. 267, 4912–4916 (2000). doi:10.1046/j.1432-1327.2000.01597.x 32. Schulz, J.B., Lindenau...
Astrocyte-Neuron Interaction at Tripartite Synapses. Astrocytes, classically considered as supportive cells for neurons without a direct role in brain information processing, are emerging as relevant elements... Pérez-Alvarez,Alberto,Araque,... - 《Current Drug Targets》 被引量: 47发表: 2013年 ...
Conserved neuron-to-astrocyte interaction In addition to these conserved mechanisms, we found that neurotensin, which modulates associative memory in the paraventricular thalamus-to-BLA circuit66, was expressed in TRAPed Syt6-positive excitatory neurons of both the mPFC and the BLA (Extended Data Fig...
A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction Institute for Basic Science Fig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acetate...
An ascorbic acid metabolic switch has been proposed as another level of interaction between antioxidant mechanisms and neuroenergetic pathways (Castro et al., 2009). According to this model, astrocytes release the antioxidant molecule ascorbic acid in response to glutamatergic activity. This ascorbic aci...
However no in vivo study reported whether there was contact interaction between astrocytes and neurons yet. In this study, mediated by Adeno- associated virus (AAV), exogeneous enhanced green fluorescent protein (EGFP) was expressed specifically in astrocytes in mouse cortex. Surprisingly EGFP was ...
Overall, the different metabolite changes observed with the two SOD1cell types highlight the role of the astrocyte-motor neuron interaction in the resulting metabolic phenotype, requiring further examination of altered met abolic pathways and their impact on motor neuron survival. 展开 ...
[15,20,21,22], a severe mental illness leading to cognitive impairments and psychosocial alterations. In addition to the reported decreased social interaction and impaired emotional information processing [23], MDD is associated with alterations in attention, executive functions and learning and memory...
Abstract Astrocytes have long been considered as just providing trophic support for neurons in the central nervous system, but recently several studies have highlighted their importance in many functions such as neurotransmission, metabolite and electrolyte homeostasis, cell signaling, inflammation, and synap...