Astrocytes in the epileptic brain. Neuron . 2008; 58 (2):168–178. doi: 10.1016/j.neuron.2008.04.002. [ Cross Ref ]Wetherington J, et al. Astrocytes in the epileptic brain. Neuron. 2008; 58 :168–78.Wetherington J, Serrano G, Dingledine R. Astrocytes in the epileptic brain. Neuron ...
67, 120 For example, astrocytes undergo remodeling in the epileptic brain, which includes both morphological and functional changes.121, 122 Astrocytes are also important for pathogenesis of various psychiatric disorders. The astrocytes may play an important role in schizophrenia, because failures in ...
11.Epileptic discharge, in turn, triggers a second activation of astrocytes that may favour seizure propagation. 癫痫放电促使星形细胞瘤第二次激活,这可能会使癫痫扩散。 12.In collaboration with Helena Parkington, a physiologist at Monash University, the team created brain tissues containing not only ...
Genetic knockout of APOE inhibited LARA formation and seizure activities in epileptic mice. Single-nucleus RNA sequencing in TLE patients confirmed the existence of a LARA subpopulation with a distinct molecular signature. Functional studies in epilepsy mouse models and human brain slices showed that ...
Expression of Multidrug Transporters MRP1, MRP2, and BCRP Shortly after Status Epilepticus, during the Latent Period, and in Chronic Epileptic Rats Summary: Purpose: Overexpression of multidrug transporters may play a role in the development of pharmacoresistance by decreasing extracellular drug levels....
The brain microenvironment has emerged as an important component in malignant progression of human glioma. However, astrocytes, the most abundant glial cells in the glioma microenvironment, have as yet a poorly defined role in the development of this disease, particularly with regard to invasion. Her...
Conclusion TNF-αsecreted by activated astrocytes could induce the seizure of rats. The change in the expression of GABA might by closely related to epileptic actions. 展开 关键词: astrocyte tumor necrosis factor epilepsy gamma-aminobutyric acid 被引量: 1 ...
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis and defence of the central nervous system (CNS). Astroglia contribute to the pathophysiology of all neurological and neuropsychiatric disorders in ways that can b
美 英 n.星形(胶质)细胞 网络星形胶质细胞;星状细胞;星形胶细胞 复数:astrocytes 英汉 英英 网络释义 n. 1. 星形(胶质)细胞
7 In conclusion to their review, the authors write that “astrocytes can hypothetically contribute to epileptogenesis by any of three routes: (1) the initiation of neuronal hyperactivity in previously normal neurons, (2) the promotion of epileptic bursting in abnormal neurons, and (3) the ...