Perhaps, the development of astrocyte-based epilepsy therapies will reduce the rate of refractory epilepsy where neuron-focused approaches have failed. In normal healthy conditions, astrocytes are in a constant state of active participation in the function of neural circuits; however, various pathologies...
Astrocytes have long been considered as just providing trophic support for neurons in the central nervous system, but recently several studies have highlig... G Ricci,L Volpi,L Pasquali,... - 《Journal of Biological Physics》 被引量: 164发表: 2009年 Integrated Brain Circuits: Astrocytic Networks...
Through computational modeling, we have shown in previous work that upregulated mGluRs on astrocytes can give rise to positive feedback in closed loop neuron-astrocyte circuits with epilepsy-type spontaneous neuronal spiking. In this paper we further quantify the necessary degree of upregulation of ...
Monitoring activity in neural circuits with genetically encoded indicators. Frontiers in Molecular Neuroscience 2014; 7: 97. 67 Revzin A, Sekine K, Sin A. Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes. Lab on a Chip. 2005; 5: 30–37...
Astrocyte cells form the largest cell population in the brain and can influence neuron behavior. These cells provide appropriate feedback control in regulating neuronal activities in the Central Nervous System (CNS). This paper presents a set of equation