In the case of astrocytes, this is the case. One direction of research, extremely important for understanding brain function, has focused on the physiology of astrocytes and their involvement in the regulation of synaptic activity of neurons. Research in the other direction has involved the study ...
The pivotal involvement of astrocytes in brain function during disease situations is the topic of many studies.Here, we will review the role of astrocytic... F Kirchhoff,R Dringen,C Giaume - 《European Archives of Psychiatry & Clinical Neuroscience》 被引量: 261发表: 2001年 The Role of Glia...
A. Reactive astrocytes: production, function, and therapeutic potential. Immunity 46, 957–967 (2017). Article CAS PubMed Google Scholar Lanjakornsiripan, D. et al. Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers. Nat. Commun...
A wide variety of specific functions has been attributed to these cells in the last 20 years. Molecular studies of these cells show that they play a key role in transmitting information in the nervous system. This 2-part review aims to analyse the function of astrocytes in mechanisms ...
Such changes can be grossly identified as reactivity, atrophy with loss of function and pathological remodeling. We outline the pathogenic potential of astrocytes in variety of disorders, ranging from neurotrauma, infection, toxic damage, stroke, epilepsy, neurodevelopmental, neurodegenerative and ...
Astrocytes are the most abundant cell type in the central nervous system, have diverse physiological roles in both health and disease, and exhibit phenotyp... LS Chaboub,B Deneen - 《Developmental Neuroscience》 被引量: 87发表: 2012年 Astrocytes and Brain Function: Implications for Reproduction Re...
Multimodal astrocyte–neuron communications govern brain circuitry assembly and function1. For example, through rapid glutamate release, astrocytes can control excitability, plasticity and synchronous activity2,3 of synaptic networks, while also contribu
sodium bicarbonate cotransporter 1, NBCe1. These results show that astrocytes maintain local brain extracellular pH homeostasis via a neuronal activity-dependent release of bicarbonate. The data provide evidence of another important metabolic housekeeping function of these glial cells....
While astrocytes certainly contribute to classic inflammatory processes (e.g. cytokine release, waste clearance, and tissue repair), newly emerging technologies for measuring and targeting cell specific activities in the brain have uncovered essential roles for astrocytes in synapse function, brain ...
He assumed that it was this to be the connective tissue of the brain and described it as "Nervenkitt". Virchow assigned to two major roles to these cell types: support function for the nerve cells involvement in tissue repair A long time it was not recognized that the so called "Nerven...