astrocyteastrocyte-to-neuroncentral nervous systemin vivonerve regenerationneurological disordersreprogrammingreviewThe inability of damaged neurons to regenerate within the mature central nervous system(CNS)is a significant neuroscientific challenge.Astrocytes are an essential component of the CNS and participate...
Ricci G, Volpi L, Pasquali L, Petrozzi L, Siciliano G (2009) Astrocyte-neuron interactions in neurological disorders. J Biol Phys 35:317–336.Ricci G, Volpi L, Pasquali L, Petrozzi L, Siciliano G. Astrocyte-neuron interactions in neurological disorders. J Biol Phys. 2009;35(4):317–36....
Further experiments should reveal additional mechanisms for astrocyte–neuron interactions in the striatum and potentially reveal insights into the functions of astrocytes in neural circuits more generally.Section snippets Astrocytes and Neural Circuits Documented over 150 years ago [1], astrocytes are part...
Valenza M, Marullo M, Di Paolo E, Cesana E, Zuccato C, Biella G, Cattaneo E (2015) Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease. Cell Death Differ 22: 690 - 702Valenza M, Marullo M, Di Paolo E, Cesana E, Zuccato C, Biella...
Perhaps, the development of astrocyte-based epilepsy therapies will reduce the rate of refractory epilepsy where neuron-focused approaches have failed. In normal healthy conditions, astrocytes are in a constant state of active participation in the function of neural circuits; however, various pathologies...
Single cell RNA-sequencing of the AstTau neuron-asteroid tau assembloid model reveals excitatory neuron inflammatory signatures and an astrocytic heat shock response similar to that occurring in the brains of individuals with tauopathies, which can be ameliorated with a neuroprotective HSP90 inhibitor. ...
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. ALS is believed to be a non-cell autonomous condition, as other cell types, including astrocytes, have been implicated in disease pathogenesis. Hence, to facilitate the development of therapeutics against ALS, it is cruci...
neuronesWe looked at the possible interactions between astrocytes and neurones during reperfusion using an in vitro model of ischaemia–reperfusion injury, as a controlled environment that lends itself easily to manipulation of the numerous variables involved in such an insult. We con...
ANLS (astrocyte neuron lactate shuttle)The metabolic events underlying neuronal activity still remain the object of intense debate, in spite of the ... S.,Mangia,F.,... - 《Journal of Neuroscience Research》 被引量: 23发表: 2010年 CrossTalk proposal: an important astrocyte‐to‐neuron lactate...
NIH 2007R37 NS Astrocyte-Neuron SignalingHaydon, Philip G. / University of Pennsylvania $385,332 NIH 2006R37 NS Astrocyte-Neuron SignalingHaydon, Philip G. / University of Pennsylvania $384,163 NIH 2005R37 NS Astrocyte-Neuron SignalingHaydon, Philip G. / University of Pennsylvania $371,064 NIH...