Astrocyte elevated gene-1 (AEG-1) is an oncogene and a critical signaling molecule that has a wide variety of interactions with other oncogenes and tumor suppressor genes, leading to increasing malignant properties of malignant gliomas, such as invasion, angiogenesis, metastasis, and chemoresistance....
Astrocyte elevated gene-1(AEG-1) induces epithelial-mesenchymal transition in lung cancer through activating Wnt/β-catenin signaling. BMC Cancer. 2015;15:1124.He W, He S, Wang Z, et al. Astrocyte elevated gene-1 (AEG-1) induces epithelial-mesenchymal transition in lung cancer through ...
Expression of astrocyte elevated gene-1 (AEG-1) as a biomarker for aggressive pancreatic ductal adenocarci- noma. BMC Cancer. 2014;14:479.Huang Y, Ren GP, Xu C, Dong SF, Wang Y, Gan Y, Zhu L and Feng TY: Expression of astrocyte elevated gene-1 (AEG-1) as a biomarker for ...
摘要: Identification and cloning of human astrocyte genes displaying elevated expression after infectionwith HIV-1 or LYRIC/AEG-1 over- expression modulates BCCIPalpha protein levels in prostatetumor cells. Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with...
High expression of astrocyte elevated gene-1 (AEG-1) is associated with progression of cervi- cal intraepithelial neoplasia and unfavorable prognosis in cervical cancer. World J Surg On- col 2013; 11: 297.Huang K, Li LA, Meng Y, You Y, Fu X, Song L. High expression of astrocyte ...
Kikuno N, Shiina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, et al. Knockdown of astrocyte-elevated gene-1 inhibits prostate can- cer progression through upregulation of FOXO3a activity. Oncogene. 2007;26:7647-55.Kikuno N,Shiina H,Urakami S,et al.Knockdown of astrocyte-elevated gene-1...
Astrocyte elevated gene-1 (AEG-1), also known as metadherin, 3D3, and lysine-rich carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) coisolated, has emerged as an important oncogene that is overexpressed in a variety of cancers. Previous studies revealed that AEG-1 is also in...
Astrocyte elevated gene-1在神经母细胞瘤中的表达及基因沉 默对细胞生物学行为的影响 姓名:刘海燕 申请学位级别:博士 专业:儿科学 指导教师:孙若鹏 20090415 在神经母细胞瘤中的表达及基因沉默对细胞生物学行为的影响中文摘要博士生:刘海燕专业:儿科学导师:孙若鹏教授研究背景神经母细胞瘤,瞧鹪从谏窬馀卟愕脑忌窬...
Astrocyte elevated gene-1 promotes hepatocarcino- genesis: novel insights from a mouse model. Hepatology 2012;56: 1782-1791.Srivastava J,Siddiq A,Emdad L. Astrocyte elevated gene-1 promotes hepatocarcinogenesis:novel insights from a mouse model[J].{H}HEPATOLOGY,2012,(5):1782-1791....
Astrocyte elevated gene-1/Metadherin (AEG-1/MTDH) augments lipid accumulation (steatosis), inflammation, and tumorigenesis, thereby promoting the whole spectrum of this disease process. Targeting AEG-1 is a potential interventional strategy for nonalcoholic steatohepatitis (NASH) and HCC. Thus, proper...