Reactive gliosisEntorhinal cortex lesionPhotothrombotic modelHypoxiaOxygen–glucose deprivationExperimental modelsAstrocyte activation and reactive gliosis are seen in many neuropathologies, e.g., neurotrauma, stroke, epilepsy, or neurodegenerative diseases. Astrocyte activation alters gene expression and leads....
摘要: Astrocyte activation and reactive gliosis are seen in many neuropathologies, e.g., neurotrauma, stroke, epilepsy, or neurodegenerative diseases. Astrocyte activation alters gene expression and leads...关键词: Astrocytes Intermediate filaments GFAP Vimentin Reactive gliosis Entorhinal cortex lesion...
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We demonstrated the ability of PDGF isoforms to induce PI3K activation and generate a ZC3H14-dependent neuroprotective effect. However, the diverse factors present in ACM suggest that in situ multiple secreted signals could be integrated through diverse receptors to activate PI3K and initiate this ...
and GLT-1 is an indirect effect, mediated via activation of other cellular signaling pathways. Studies have shown that growth factors such as TGF-α and TGF-β are vital to this E2 action on glutamate transporters (Lee et al., 2009a, 2012b). Thus, the goal of this review is to shed...
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