Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse functions in health and disease. Astrocyte dysfunction is found in numerous diseases, including multiple sclerosis, Alzheimer disease, Parkinson disease, Huntington disease and neuropsychiatric disorders. Astrocytes ...
The role of glial cells in brain function is receiving renewed interest. Recent studies show that astrocytes, a subtype of glial cell, regulate neuronal excitability and synaptic transmission. Astrocytes regulate inhibition through a glial adenosine cycle and by providing glutamine, a precursor for the...
scholar's research in astrocyte have made giant strides.The new function and affect of astrocytes have been found and proved gradually.This thesis,reviews the normal biological function and the recent progress of astrocytes' biological function and discusses the relation between astrocyte and some ...
glial cells were considered to play a supportive role in CNS instead of information processing.Recently,a variety of studies suggest that glial cells are actively involved in the regulation of brain function associated with neurons.Glial cells,especially astrocytes play important roles in different ...
impairment in AD47,48, and functional abnormalities in GLT-1 induce synaptic loss49. In the present study, reactive astrocytes in the AD-D group showed weak GLT-1 expression in spite of a higher number of cells, suggesting that these reactive astrocytes may not function adequately in the ...
Altered glial cell function occurring in substantia nigra in Parkinson' disease may lead to the release of cytokines and impairment of neurotrophic factor production, which in turn, may cause dopaminergic apoptosis. To evaluate this concept, primary cultures of rat brain astrocytes were activated with...
Following focal cerebral ischemia ("stroke") a complex and dynamic interaction of vascular cells, glial cells, and neurons determines the extent of the ens... G Trendelenburg,U Dirnagl - 《Glia》 被引量: 486发表: 2010年 Astrocytic A1/A2 paradigm participates in glycogen mobilization mediated ne...
会议名称: 6th European Meeting on Glial Cell Function in Health and Disease 会议时间: 2003/09/01 收藏 引用 批量引用 报错 分享 全部来源 求助全文 ResearchGate 相似文献Oligodendrocyte Precursor Cells Reprogrammed to Become Multipotential CNS Stem Cells cells to revert to multipotential neural stem ...
Neurons that produce gonadotropin-releasing hormone (GnRH), which control fertility, complete their nose-to-brain migration by birth. However, their function depends on integration within a complex neuroglial network during postnatal development. Here, w
“shell” 3D surfaces were then created using an Imaris XTension function generated at the Washington University Center for Cellular Imaging. Plaque surfaces were dilated either 30 µm or 50 µm and new surfaces were generated as 30 µm shells and 50 µm shells. Astrocyte and dystrophic...