Exons are coding sections of an RNA transcript, or the DNA encoding it, which are translated into a proteinexon / exonsexon, exonsScitable
On the basis of clinical examination, Belgian and Dutch control individuals had no neurological or psychiatric antecedents and were subjects without organic disease involving the CNS. Genomic DNA of patients was systematically screened for mutations in the coding exons of four dementia genes—PSEN1 (MIM...
The yield of major crops is generally limited by sink capacity and source strength. Cucumber is a typical raffinose family oligosaccharides (RFOs)–transporting crop. Non-coding RNAs and alternative polyadenylation (APA) play important roles in the regul
Long noncoding RNAs (lncRNAs) are emerging as key regulators of genetic and epigenetic networks, and their deregulation may underlie complex diseases, such as carcinogenesis. Several studies described lncRNA alterations in patients with solid tumors. In particular, HOTAIR upregulation has been associate...
Database searches with the glomulin-coding sequence did not identify either a signal sequence or any other functional or conserved domain. Partial sequence identity with exons 6–11 was found in DNA from human chromosome 21, but no corresponding ESTs could be retrieved. Thus, this partial paralog...
. In T cells, almost half of LINE1 reads were chimeric (that is, mapping to both LINE1 and a nonrepetitive region), and the majority of reads derived from LINE1 localized to protein-coding genes (Extended Data Fig.2d,e), thus most likely included in non-canonical transcript variants. ...
a, Schematic diagrams of the mouseXcr1WT allele, the targeting vector (IRES-mCherry-T2a-hCRE with FRT flanked pGK-Neo cassettes), and the targeted allele. Filled and open boxes denote coding and noncoding exons ofXcr1, respectively.b, Southern blot analysis ofXcr1+/+andXcr1Cre/+.Genomic...
Filled and open boxes denote coding and noncoding exons of Xcr1, respectively. b, Southern blot analysis of Xcr1+/+ and Xcr1Cre/+. Genomic DNAs were isolated from mice tails, digested with SalI, electrophoresed, and hybridized with the 5′-radiolabelled probe indicated in a. Southern ...
Overlapping exons may thus be a key obstacle to improving recall of many short-read RI detection tools. Persistent introns or called RIs occur in genes with experimentally validated IR Finally, we searched the literature and third-party resources for independent evidence of persistent introns ...
In the package annotatR, we searched for enrichment in coding regions, intergenic regions, exons, introns, 3UTR, CpG shores, shelves and islands. Using ChIPseeker, we searched for enrichment in the default regions: promoter, 5’UTR, 3’UTR, exons, introns, and intergenic regions. We refined ...