英文名称 AP-1/NF-κB activation inhibitor 1 生化机理 AP-1/NF-κB 激活抑制剂 1 是一种强效的 AP-1 和 NF-κB 介导的转录激活抑制剂(IC 50 =1 μM),不会阻断由 β-肌动蛋白启动子驱动的基础转录。AP-1/NF-κB 激活抑制剂 1 也有类似的抑制作用。 储存温度 -80℃储存 运输条件 超低温冰袋...
as well as to suppress the expression of inflammatory factors, such, that play an important role in the expression of inflammatory factors, cell proliferation and natural causes such as IL-1尾 it significantly inhibits the activity, may be usefully used as an AP-1 inhibitors for inflammatory dis...
AP-1/NF-κB activation inhibitor 1 | MCE 英文名称: 总访问: 193 国产/进口: 进口 半年访问: 19 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg 最后更新: 2025-2-13 货号: HY-133987 CAS 号: 188936-12-1 参考报价: 2200; 2000; 3000;...
AP-1 inhibitor induces ferroptosis via the PI3K/AKT pathway in multiple myeloma cells Multiple myeloma (MM) is an incurable malignancy of plasma cells that is sensitive to T-5224, an AP-1 inhibitor. Previous study indicated that T-5224 inhib... S Tang,J Liu,F Li,... - 《Heliyon》 被...
文献：Wang H, Ma C, Liu C, Sun L, Wang Y, Xue J, Zhao B, Dong W. The c-Fos/AP-1 inhibitor inhibits sulfur mustard-induced chondrogenesis impairment in zebrafish larvae. Chemosphere. 2024 May 16:142299. doi: 10.1016/j.chemosphere.2024.142299. Epub ahead of print. PMID: 38761826....
可任选与本发明的式I化合物联用的降血脂药或降脂药或调脂药包括1、2、3或更多种MTP抑制剂、HMG CoA还原酶抑制剂、角鲨烯合成酶抑制剂、苯乙酸衍生物、ACAT抑制剂、脂氧化酶抑制剂、胆固醇吸收抑制剂、回肠Na+/胆汁酸协同转运蛋白抑制剂(ileal Na+/bile acid cotransporterinhibitor)、LDL受体活性上调剂、胆汁酸多...
Basal cell carcinomas (BCCs) depend on Hedgehog (Hh)/Gli signaling, but can develop mechanisms of Smoothened (SMO) inhibitor resistance. We previously identified a nuclear myocardin-related transcription factor (nMRTF) resistance pathway that amplifies noncanonical Gli1 activity, but characteristics and...
A-FABP Inhibitor|ALBP Inhibitor|Adipocyte FABP Inhibitor|BMS 309403|Fatty Acid Binding Protein 4 Inhibitor|aP2 Inhibitor; 2-[[2'-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1'-biphenyl]-3-yl]oxy]-acetic acid 供应商 Cayman Chemical ...
AP-1/NF-kB Dual Inhibitor, SP100030 会员价请登录市场价￥2211 原厂型号5.31535.0001 贝雷猫货号RH156059 品牌默克密理博/Millipore 单件重量1kg 货期45天 单位:盒包装:盒库存:0 数量:盒+-1盒起订,增量1盒 累计成交0笔0条评价 选择其它规格 商品名 ...
RANKL与RANK结合后,TRAF6结合到RANKL的细胞质区,NF-κB抑制物激酶(inhibitor of NF-κB kinases,IKKs) 被激活,启动信号通路,激活NF-κB,活化的 NF-κB转移到细胞核内,NF-κB的p50和p65亚基因诱导c-fos、NFATc1 表达增加,c-fos与NFATc1 相互作用,引起破骨细胞基因的转录与表达,诱导破骨细胞生成[22]。基因...