In addition to the titer, the test may also report the localization pattern for the antibody observed under a microscope, which can provide insights into potential autoimmune conditions. Common patterns include homogeneous, speckled, and nucleolar, each associated with different diseases. It's important...
2007. Relevance of the immunofluorescence pattern for interpretation of the ANA test: the case of the dense fine speckled pattern. Rev Assoc Med Brasil 53: 439-445.Dellavance A; Leser PG,Andrade LE; Relevance of the immunofluorescence pattern for interpre tation of the ANA test-the case of ...
The presence of ANA with a homogeneous & speckled (HS) pattern wassignificantly associated with the absence of cancer(p < 0.01). Patients with a HS pattern were found to have a lower relative risk (RR 0.7, 95%CI 0.5-0.9) of having cancer compared to those with other patterns. ...
The burden of the variability introduced by the HEp-2 assay kit and the CAD system in ANA indirect immunofluorescence test Article 25 July 2016 Recognition of the dense fine speckled (DFS) pattern remains challenging: results from an international internet-based survey Article Open access 09 ...
SSB为SS的B抗原, MCTD——混合性结缔组织病(mixed connective tissue disease) SS——干燥综合征(Sjogren’s syndrome) PM/DM——(ploymyositis)多发性肌炎/皮肌炎(dermatomyositis) PSS——进行性系统性硬化症(progressive systemic sclerosis) Speckled ANA HEp-2 cell IIF Sometimes when performing the ANA test,...
(A) Dense fine speckled pattern of the interphase nuclei (1) as well as of the metaphase chromatin (2) of a DFS70 antibody; (B) classic homogeneous ANA pattern of a dsDNA antibody with homogeneous-peripheral staining of the interphase nuclei (1) as well as of the chromatin in all mitoti...
Monospecific anti-DFS70 antibodies are moderately helpful in excluding ANA-associated rheumatic disease in patients presenting with a dense fine speckled pattern - A systematic review and meta-analysis of diagnostic test accuracy 来自 NCBI 喜欢 0 阅读量: 10 ...
Up to 20% of serum samples from HI have been reported to have a positive ANA IIF test, the majority of them due to the presence of anti-dense fine speckled 70 (anti-DFS70) antibodies. Monospecific anti-DFS70 antibodies represent a biomarker that can be used to discriminate AARD patients...
• Pattern –speckled - + ENA’s –rim - ds DNA –homogeneous - DNA (LE prep) –nucleolar - Scl - 70 SLE SLE Tissue Specific Nuclear Antibodies Antibodies ATA Ro/SSA Anti ASMA La/SSB Anti-MITO RNP Anti-LKM Sm Anti-PC ds DNA ...
Thomas K. BurnhamD'Anne M. KleinsmithElsevier Inc.Seminars in Arthritis and RheumatismBurnham, T.K. and Kleinsmith, D.M. (1983) . The "true speckled" antinuclear antibody (ANA) pattern its tumultaous history . Semin. Arth. Rheum. 13 : 155-159....