1. **均质型（homegeneouspattern, H）**：分裂间期细胞核质染色均匀一致，分裂期细胞染色质阳性。与抗DNP抗体、抗dsDNA抗体、抗组蛋白抗体和抗核小体抗体相关。2. **斑点型（speckledpattern, S）**：分裂间期细胞核质染色呈斑点状、斑块状，核仁阴性；分裂期细胞染色质阴性。常见于抗可溶性核抗原(EN...
(1)均质型(homegeneouspattern,H) 又称弥散型。分裂间期细胞核质染色均勻一致,分裂期细胞染色质阳性(亦呈均质型)。此染色型与抗DNP抗体、抗dsDNA抗体、抗组蛋白抗体和抗核小体抗体有关。(2) 斑点型(speckledpattern, S) 又称核颗粒型、核斑块型。分裂间期细胞核质染色呈斑点状、斑块状,核仁阴性;分裂期细胞染色...
ANA Screen ( lF ) Positive...ANA Screen ( lF ) Positive 1:100Speckled Pattern2...
speckled pattern; nucleolar pattern; and peripheral or rim pattern. While these patterns are not specific to any one illness, certain illnesses can more frequently be associated with one pattern or another. The patterns can sometimes give the doctor further clues as to the types of illnesses to ...
2.斑点型(speckled pattern,S):又称核颗粒型、核斑块型。和细胞核可溶性核蛋白物质ENA,其相关疾病为硬皮病(SSc)、干燥综合征(SS)、多发性肌炎/皮肤炎(PM/DM)、系统性红斑狼疮(SLE)、类风湿关节炎(RA)等。3.核仁型(nuclear pattern,N):核仁颗粒型常与抗U3nRNP/Fibrillarin抗体、抗RNA多聚酶I抗体相关;核仁...
(2 )斑点型(speckled pattern , S ):又称颗粒型,核斑块型。核质染色呈斑点状.斑块状,核仁阴性,中期细胞染色质阴性。此荧光染色模型与可溶性抗原(ENA)抗体有关。 (3 )核仁型(nucleolar pattern , N ):核仁着染荧光,中性细胞染色质阴性。核仁颗粒型,常与抗U 3nRNP/Fibrillarin抗体、抗RNA多聚酶I抗体相关;仁...
Background The clinical significance of Dense Fine Speckled (DFS) pattern Anti-nuclear antibodies (ANA) by indirect immunofluorescence method (IIF) is unclear and has been inversely associated with rheumatic disease 1 2.Objectives Our purpose was to determine associations between DFS pattern ANA and ...
Speckled: Fine and coarse speckles of ANA staining are seen throughout the nucleus. This pattern is more commonly associated with antibodies to extractable nuclear antigens. This pattern can be associated with Systemic Lupus Erythematosus, Sjögren’s syndrome, Systemic Sclerosis, Polymyositis, and Rh...
The “true Speckled” antinuclear antibody (ANA) pattern: Its tumultuous history☆Author links open overlay panelThomas K. Burnham 1, D'Anne M. Kleinsmith 1Show more Add to Mendeley Share Cite https://doi.org/10.1016/0049-0172(83)90001-XGet rights and contentAccess through your organization ...
The presence of ANA with a homogeneous & speckled (HS) pattern was significantly associated with the absence of cancer (p < 0.01). Patients with a HS pattern were found to have a lower relative risk (RR 0.7, 95%CI 0.5-0.9) of having cancer compared to those with other patterns. Can ...