常出现在SLE病人血清中,特别是SLE活动期病人血清中。2.斑点型(speckled pattern,S):又称核颗粒型、核斑块型。和细胞核可溶性核蛋白物质ENA,其相关疾病为硬皮病(SSc)、干燥综合征(SS)、多发性肌炎/皮肤炎(PM/DM)、系统性红斑狼疮(SLE)、类风湿关节炎(RA)等。3.核仁型(nuclear pattern,N):核仁颗粒型常与抗U3...
Antinuclear antibody indirect immunofluorescence (ANA IF) positive using cytobead ANA with a homogenous pattern and cytoplasmic speckled titer 1/80. Confirmation beads showed positive of dsDNA only. ANA profile showed positive antinucleosome, antihistone, and AMA-M2, and also increased anti...
For example, the nucleolar pattern is more commonly seen in the disease scleroderma, while the homogeneous pattern is often associated with systemic lupus erythematosus (SLE). The ANA speckled pattern, on the other hand, is seen in many conditions including Sjögren's syndrome and mixed ...
此荧光染色型与抗核层蛋白(1amin)抗体相关.有学者 认为,由于抗原底物片固定方法或制备过程中的影响,某些抗 dsD.NA 抗体亦呈榜膜型,中期细胞荧光染色质阴性或呈周边 型.(5)着丝点型(centrcmerepattern):又称散在斑点型(discrtc speckledpattern).孩内均匀散布大小较一致的着染荧光细颗粒 (4o～60 个),无核...
(ANA) HomogeneousPattern 6 Anti-NuclearAntibody(ANA) RimPattern CLS420ClinicalImmunology&MolecularDiagnostics–LectureSeries Immunity&AutoimmuneDiseases2 7 Anti-NuclearAntibody(ANA) SpeckledPattern 8 Anti-NuclearAntibody(ANA) NucleolarPattern 9 Anti-NuclearAntibody(ANA) CentromerePattern Thecentromerepatternhas...
Seventy-seven to 80% of the laboratory professionals and 61–64% of the clinicians scored the clinical relevance of the nuclear speckled pattern (AC-2,4,5) and nucleolar pattern (AC-8,9,10) high. In contrast, only 41% of laboratory professionals and 35% of clinicians scored the clinical...
ANA检测的质量控制 Venus Williams 1980.6.17 185 cm, 75 kg 43 champing titles 597 win / 147 lost Michael Jackson 1958.8.29 -2009.6.25180cm, 60kg 6
Monospecific anti-DFS70 antibodies are moderately helpful in excluding ANA-associated rheumatic disease in patients presenting with a dense fine speckled p... CF Cheng,T Lan,M Shih,... - 《Autoimmunity Reviews》 被引量: 0发表: 2020年 Antineutrophil cytoplasmic autoantibody-associated alveolar ...
Figure 1: Differentiation of “homogeneous” ANA patterns on HEp-2 cells (left: overview; right: metaphase cells). (A) Dense fine speckled pattern of the interphase nuclei (1) as well as of the metaphase chromatin (2) of a DFS70 antibody; (B) classic homogeneous ANA pattern of a dsDNA...
2.斑点型(speckled pattern,S):又称核颗粒型、核斑块型。和细胞核可溶性核蛋白物质ENA,其相关疾病为硬皮病(SSc)、干燥综合征(SS)、多发性肌炎/皮肤炎(PM/DM)、系统性红斑狼疮(SLE)、类风湿关节炎(RA)等。3.核仁型(nuclear pattern,N):核仁颗粒型常与抗U3nRNP/Fibrillarin抗体、抗RNA多聚酶I抗体相关;核仁...