In addition to the titer, the test may also report the localization pattern for the antibody observed under a microscope, which can provide insights into potential autoimmune conditions. Common patterns include homogeneous, speckled, and nucleolar, each associated with different diseases. It's important...
Thomas K. BurnhamD'Anne M. KleinsmithElsevier Inc.Seminars in Arthritis and RheumatismBurnham, T.K. and Kleinsmith, D.M. (1983) . The "true speckled" antinuclear antibody (ANA) pattern its tumultaous history . Semin. Arth. Rheum. 13 : 155-159....
Homogenous:The entire nucleus is stained with ANA. This is the most common pattern and can be seen with any autoimmune disease. Homogenous staining can result from antibodies to DNA and histones. Speckled: Fine and coarse speckles of ANA staining are seen throughout the nucleus. ...
Cytoplasmic AC patterns were less frequently used in ANA IIF test result reporting than nuclear AC patterns. Among the competent cytoplasmic patterns (fibrillar (AC-15,16,17), speckled (AC-18,19,20), reticular/ mitochondria-like (AC-21), polar/Golgi-like (AC-22), rods and rings (AC-23...
Monospecific anti-DFS70 antibodies are moderately helpful in excluding ANA-associated rheumatic disease in patients presenting with a dense fine speckled pattern - A systematic review and meta-analysis of diagnostic test accuracy 来自 NCBI 喜欢 0 阅读量: 10 ...
• Pattern –speckled - + ENA’s –rim - ds DNA –homogeneous - DNA (LE prep) –nucleolar - Scl - 70 SLE SLE Tissue Specific Nuclear Antibodies Antibodies ATA Ro/SSA Anti ASMA La/SSB Anti-MITO RNP Anti-LKM Sm Anti-PC ds DNA ...
2007. Relevance of the immunofluorescence pattern for interpretation of the ANA test: the case of the dense fine speckled pattern. Rev Assoc Med Brasil 53: 439-445.Dellavance A; Leser PG,Andrade LE; Relevance of the immunofluorescence pattern for interpre tation of the ANA test-the case of ...