The specific fluorescence pattern can also help identify the type of autoimmune disease, as different conditions have distinct staining patterns. It's important to recognize that a positive ANA test can occur in various situations, including chronic infections, malignancies, and even in healthy ...
Thomas K. BurnhamD'Anne M. KleinsmithElsevier Inc.Seminars in Arthritis and RheumatismBurnham, T.K. and Kleinsmith, D.M. (1983) . The "true speckled" antinuclear antibody (ANA) pattern its tumultaous history . Semin. Arth. Rheum. 13 : 155-159....
The presence of ANA with a homogeneous & speckled (HS) pattern wassignificantly associated with the absence of cancer(p < 0.01). Patients with a HS pattern were found to have a lower relative risk (RR 0.7, 95%CI 0.5-0.9) of having cancer compared to those with other patterns. ...
Except for dense fine speckled (DFS), the nuclear competent patterns were reported by > 85% of the laboratories. Except for rods and rings, the cytoplasmic competent patterns were reported by > 72% of laboratories. Cytoplasmic IIF staining was considered ANA positive by 55% of ...
PM/Scl pattern Clumpy-nucleolar pattern Scl 70 pattern NOR pattern ? Most nucleolar patterns are associated with nuclear patterns.CAUTION: falsely positive nucleolar patterns are among the most common artifacts in HEp-2 testing and are usually caused by: ?excess of counterstain; this problem is ...
Monospecific anti-DFS70 antibodies are moderately helpful in excluding ANA-associated rheumatic disease in patients presenting with a dense fine speckled p... CF Cheng,T Lan,M Shih,... - 《Autoimmunity Reviews》 被引量: 0发表: 2020年 Antineutrophil cytoplasmic autoantibody-associated alveolar ...
IIF on HEp-2 cells for ANA remains the "gold standard" but it has very low positive predictive value. Up to 20% of serum samples from HI have been reported to have a positive ANA IIF test, the majority of them due to the presence of anti-dense fine speckled 70 (anti-DFS70) ...
Pattern on the antinuclear antibody-HEp-2 test is a critical parameter for discriminating antinuclear antibodypositive healthy individuals and patients with autoimmune rheumatic diseases. Arthritis Rheum 2011;63:191–200.10.1002/art.30084Suche in Google Scholar 11. Ochs RL, Stein TW, Peebles CL, ...
• Pattern –speckled - + ENA’s –rim - ds DNA –homogeneous - DNA (LE prep) –nucleolar - Scl - 70 SLE SLE Tissue Specific Nuclear Antibodies Antibodies ATA Ro/SSA Anti ASMA La/SSB Anti-MITO RNP Anti-LKM Sm Anti-PC ds DNA ...
2007. Relevance of the immunofluorescence pattern for interpretation of the ANA test: the case of the dense fine speckled pattern. Rev Assoc Med Brasil 53: 439-445.Dellavance A; Leser PG,Andrade LE; Relevance of the immunofluorescence pattern for interpre tation of the ANA test-the case of ...