In addition to the titer, the test may also report the localization pattern for the antibody observed under a microscope, which can provide insights into potential autoimmune conditions. Common patterns include homogeneous, speckled, and nucleolar, each associated with different diseases. It's important...
The antinuclear antibody (ANA) test has high sensitivity in diagnosing and classifying systemic lupus erythematosus (SLE).#To describe the immunological pattern of SLE patients through investigating specific antinuclear autoantibodies by enzyme dot immunoassay and studying their frequency in both positive ...
The presence of ANA with a homogeneous & speckled (HS) pattern wassignificantly associated with the absence of cancer(p < 0.01). Patients with a HS pattern were found to have a lower relative risk (RR 0.7, 95%CI 0.5-0.9) of having cancer compared to those with other patterns. ...
Monospecific anti-DFS70 antibodies are moderately helpful in excluding ANA-associated rheumatic disease in patients presenting with a dense fine speckled pattern - A systematic review and meta-analysis of diagnostic test accuracy 来自 NCBI 喜欢 0 阅读量: 10 ...
(A) Dense fine speckled pattern of the interphase nuclei (1) as well as of the metaphase chromatin (2) of a DFS70 antibody; (B) classic homogeneous ANA pattern of a dsDNA antibody with homogeneous-peripheral staining of the interphase nuclei (1) as well as of the chromatin in all mitoti...