Development of aggressive forms of prostate cancer may be influenced by environmental effects that otext editorEmerging Infectious Diseases
Two newly published studies are presenting novel diagnostic techniques to help catch the most aggressive forms of prostate cancer at an early stage. A University of East Anglia study presents an innovative way to measure gene expression in tumor samples and predict disease severity, while an Australi...
Inc., focused on developing transformative medicines in oncology utilizing artificial intelligence approaches. The subsidiary was formed in 2022 to develop BXCL701, a Phase 2, investigational, oral innate immune activator for the treatment of aggressive forms of...
Early diagnosis is pivotal to the treatment of all cancers, but some reveal their machinations far earlier than others. Prostate cancer is unfortunately one that might not show itself until in its later, more aggressive stages, so the search is on for tools that can pick it up earlier in th...
Pro forms of prostate specific antigen (PSA) have been reported to be more cancer specific markers of prostate cancer than total PSA and they also may preferentially detect the more aggressive forms of the disease. Research immunoassays with high specificity for pro-PSA forms were used to study ...
According to the documents obtained by Variety, the 60-year-old alleged that Royal Goode Productions continued to use footage of the couple in the upcoming "Tiger King 2" despite only signing appearance release forms for the first documentary. CLICK HERE TO SIGN UP FOR THE ENTERTAINMENT ...
Downregulation of miR-221 was negatively correlated with the expression of the proto-oncogen c-kit in primary carcinoma. In a large study cohort, the prostate-specific oncomir miR-221 was progressively downregulated in aggressive forms of PCa. Downregulation of miR-221 was associated with ...
Prostate cancer (PCa) shows strong dependence on the androgen receptor (AR) pathway. Here, we show that squalene epoxidase (SQLE), an enzyme of the cholesterol biosynthesis pathway, is overexpressed in advanced PCa and its expression correlates with poor
There are novel forms of hormonal therapy, or cytotoxic chemotherapy. Hormonal therapy includes agents like enzalutamide (Xtandi) or abiraterone (Zytiga), and cytotoxic chemotherapy refers to docetaxel, which has been shown to prolong survival in men with metastatic and castration-resistant prostat...
The exogenous hypoxia marker pimonidazole is a 2-nitroimidazole compound, which forms covalent bonds with cellular macromolecules at oxygen levels below 1.3% (Gross et al, 1995) and visualises poorly oxygenated regions in histological sections from tumours (Kizaka-Kondoh and Konse-Nagasawa, 2009). ...